Results 11 to 20 of about 33,239 (264)
Crossover interference mediates multiscale patterning along meiotic chromosomes. [PDF]
Nat CommunAbstractThe classical phenomenon of crossover interference is a one-dimensional spatial patterning process that produces evenly spaced crossovers during meiosis. Quantitative analysis of diagnostic molecules along budding yeast chromosomes reveals that this process also sets up a second, interdigitated pattern of related but longer periodicity, in a ...
White MA +5 more
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CODA (crossover distribution analyzer): quantitative characterization of crossover position patterns along chromosomes [PDF]
BMC Bioinformatics, 2011 Abstract Background During meiosis, homologous chromosomes exchange segments via the formation of crossovers. This phenomenon is highly regulated; in particular, crossovers are distributed heterogeneously along the physical map and rarely arise in close proximity, a property referred to as "interference".
Franck Gauthier +2 more
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Crossover patterns under meiotic chromosome program
Asian Journal of Andrology, 2021 Repairing DNA double-strand breaks (DSBs) with homologous chromosomes as templates is the hallmark of meiosis. The critical outcome of meiotic homologous recombination is crossovers, which ensure faithful chromosome segregation and promote genetic diversity of progenies.
Shunxin Wang +5 more
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Modulating crossover positioning by introducing large structural changes in chromosomes [PDF]
BMC Genomics, 2015 Crossing over assures the correct segregation of the homologous chromosomes to both poles of the dividing meiocyte. This exchange of DNA creates new allelic combinations thus increasing the genetic variation present in offspring. Crossovers are not uniformly distributed along chromosomes; rather there are preferred locations where they may take place ...
A. Ederveen +4 more
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Per-nucleus crossover covariation is regulated by chromosome organization [PDF]
iScience, 2022 Meiotic crossover (CO) recombination between homologous chromosomes regulates chromosome segregation and promotes genetic diversity. Human females have different CO patterns than males, and some of these features contribute to the high frequency of chromosome segregation errors.
Cunxian Fan +4 more
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Meiotic crossovers characterized by haplotype-specific chromosome painting in maize [PDF]
Nature Communications, 2019 AbstractMeiotic crossovers (COs) play a critical role in generating genetic variation and maintaining faithful segregation of homologous chromosomes during meiosis. We develop a haplotype-specific fluorescence in situ hybridization (FISH) technique that allows visualization of COs directly on metaphase chromosomes. Oligonucleotides (oligos) specific to
Lívia do Vale Martins +11 more
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Crossover effects of B chromosomes may be 'selfish' [PDF]
Heredity, 1994 Wayne R. Carlson
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Crossover Position Drives Chromosome Remodeling for Accurate Meiotic Chromosome Segregation [PDF]
Current Biology, 2020 Interhomolog crossovers (COs) are a prerequisite for achieving accurate chromosome segregation during meiosis [1, 2]. COs are not randomly positioned, occurring at distinct genomic intervals during meiosis in all species examined [3-10]. The role of CO position as a major determinant of accurate chromosome segregation has not been previously directly ...
Elisabeth, Altendorfer +4 more
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A new efficient genetic algorithm-Taguchi-based approach for multi-period inventory routing problem [PDF]
International Journal of Research in Industrial Engineering, 2023 The inventory routing problem arises from the combination of the vehicle routing problem and the vendor-managed inventory problem. In this paper, we present a mathematical model and a novel genetic algorithm for solving the multi-period inventory routing
Amin Farahbakhsh, Amir Saman Kheirkhah
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Meiotic chromosome organization and crossover patterns
Biology of Reproduction, 2022 Abstract Meiosis is the foundation of sexual reproduction, and crossover recombination is one hallmark of meiosis. Crossovers establish the physical connections between homolog chromosomes (homologs) for their proper segregation and exchange DNA between homologs to promote genetic diversity in gametes and thus progenies.
Yongliang, Shang +8 more
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