Results 11 to 20 of about 855,599 (268)

Sex-specific crossover distributions and variations in interference level along Arabidopsis thaliana chromosome 4. [PDF]

PLoS Genetics, 2007
In many species, sex-related differences in crossover (CO) rates have been described at chromosomal and regional levels. In this study, we determined the CO distribution along the entire Arabidopsis thaliana Chromosome 4 (18 Mb) in male and female ...
Jan Drouaud, Raphaël Mercier, Liudmila Chelysheva, Aurélie Bérard, Matthieu Falque, Olivier Martin, Vanessa Zanni, Dominique Brunel, Christine Mézard   +8 more
doaj   +2 more sources

The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

eLife, 2016
Asymmetric disassembly of the synaptonemal complex (SC) is crucial for proper meiotic chromosome segregation. However, the signaling mechanisms that directly regulate this process are poorly understood.
Saravanapriah Nadarajan, Firaz Mohideen, Yonatan B Tzur, Nuria Ferrandiz, Oliver Crawley, Alex Montoya, Peter Faull, Ambrosius P Snijders, Pedro R Cutillas, Ashwini Jambhekar, Michael D Blower, Enrique Martinez-Perez, J Wade Harper, Monica P Colaiacovo   +13 more
doaj   +2 more sources

Synchronous L1 retrotransposition events promote chromosomal crossover early in human tumorigenesis [PDF]

bioRxiv
Sonia Zumalave, Martín Santamarina, Nuria P. Espasandín, Daniel García‐Souto, Javier Temes, Toby M. Baker, Ana Pequeño‐Valtierra, Iago Otero, Jorge Rodríguez‐Castro, Ana Oitabén, Eva G. Álvarez, Paula Otero, Iria Díaz-Arias, Mónica Martínez‐Fernández, Peter Van Loo, Gaël Cristofari, Bernardo Rodríguez–Martín, José M. C. Tubío   +17 more
openalex   +2 more sources

A new efficient genetic algorithm-Taguchi-based approach for multi-period inventory routing problem [PDF]

International Journal of Research in Industrial Engineering, 2023
The inventory routing problem arises from the combination of the vehicle routing problem and the vendor-managed inventory problem. In this paper, we present a mathematical model and a novel genetic algorithm for solving the multi-period inventory routing
Amin Farahbakhsh, Amir Saman Kheirkhah
doaj   +1 more source

Resolution of Joint Molecules by RuvABC and RecG Following Cleavage of the Escherichia coli Chromosome by EcoKI [PDF]

, 2009
DNA double-strand breaks can be repaired by homologous recombination involving the formation and resolution of Holliday junctions. In Escherichia coli, the RuvABC resolvasome and the RecG branch-migration enzyme have been proposed to act in alternative ...
Leach, David, Okely, Ewa, Wardrope, Laura   +2 more
core   +12 more sources

Meiotic recombination dynamics in plants with repeat-based holocentromeres shed light on the primary drivers of crossover patterning

bioRxiv, 2023
Centromeres strongly affect (epi)genomic architecture and meiotic recombination dynamics influencing the overall distribution and frequency of crossovers.
Marco Castellani, Meng Zhang, Gokilavani Thangavel, Yennifer Mata Sucre, Thomas M. Lux, J. A. Campoy, Magdalena Marek, B. Huettel, Hequan Sun, Klaus F. X. Mayer, Korbinian Schneeberger, A. Marques   +11 more
semanticscholar   +1 more source

The impact of chromosomal fusions on 3D genome folding and recombination in the germ line

Nature Communications, 2021
The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear.
Covadonga Vara, A. Paytuví-Gallart, Yasmina Cuartero, Lucía Álvarez-González, Laia Marín-Gual, Francisca García, Beatriu Florit-Sabater, L. Capilla, R. Sánchez-Guillén, Z. Sarrate, R. Aiese Cigliano, W. Sanseverino, J. Searle, J. Ventura, M. Martí-Renom, François le Dily, A. Ruiz-Herrera   +16 more
semanticscholar   +1 more source

Regulation of interference-sensitive crossover distribution ensures crossover assurance in Arabidopsis

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Meiotic crossovers (COs) are required for accurate chromosome segregation and mix parental genomes to generate genetically diversified gametes. The distribution of COs among chromosomes is not random.
Xiang Li, Jun Zhang, Jiyue Huang, Jing Xu, Zhiyu Chen, G. Copenhaver, Yingxiang Wang   +6 more
semanticscholar   +1 more source

Demonstration of targeted crossovers in hybrid maize using CRISPR technology

Communications Biology, 2022
Kouranov et al. demonstrate Cas12a-mediated targeted chromosomal crossover (CO) in transgenic hybrid maize plants and produce heritable crossover in F1 plants when Cas12a transgene is segregated away.
Andrei Kouranov, Charles Armstrong, Ashok Shrawat, Vladimir Sidorov, Scott Huesgen, Bryce Lemke, Timothy Boyle, Michelle Gasper, Richard Lawrence, Samuel Yang   +9 more
doaj   +1 more source

Meiotic Recombination Analyses in Pigs Carrying Different Balanced Structural Chromosomal Rearrangements. [PDF]

PLoS ONE, 2016
Correct pairing, synapsis and recombination between homologous chromosomes are essential for normal meiosis. All these events are strongly regulated, and our knowledge of the mechanisms involved in this regulation is increasing rapidly.
Nicolas Mary, Harmonie Barasc, Stéphane Ferchaud, Aurélia Priet, Anne Calgaro, Anne-Marie Loustau-Dudez, Nathalie Bonnet, Martine Yerle, Alain Ducos, Alain Pinton   +9 more
doaj   +1 more source