An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans
Summary: Balancer chromosomes are critical tools for genetic research. In C. elegans, reciprocal translocations that lead to aneuploidy have been widely used to maintain lethal and sterile mutations in stable stocks.
Katsufumi Dejima +6 more
doaj +1 more source
A universal method for automated gene mapping [PDF]
Small insertions or deletions (InDels) constitute a ubiquituous class of sequence polymorphisms found in eukaryotic genomes. Here, we present an automated high-throughput genotyping method that relies on the detection of fragment-length polymorphisms ...
Basler, Konrad +6 more
core +2 more sources
Crossing over...Markov meets Mendel. [PDF]
Chromosomal crossover is a biological mechanism to combine parental traits. It is perhaps the first mechanism ever taught in any introductory biology class.
Saad Mneimneh
doaj +1 more source
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. [PDF]
Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones.
Cartman, ST +6 more
core +5 more sources
Manipulation of crossover frequency and distribution for plant breeding
The crossovers (COs) that occur during meiotic recombination lead to genetic diversity upon which natural and artificial selection can act. The potential of tinkering with the mechanisms of meiotic recombination to increase the amount of genetic ...
A. Blary, E. Jenczewski
semanticscholar +1 more source
In nature, closely related species may hybridize while still retaining their distinctive identities. Chromosomal regions that experience reduced recombination in hybrids, such as within inversions, have been hypothesized to contribute to the maintenance ...
Rob J Kulathinal +2 more
doaj +1 more source
Broad-scale recombination pattern in the primitive bird Rhea americana (Ratites, Palaeognathae). [PDF]
Birds have genomic and chromosomal features that make them an attractive group to analyze the evolution of recombination rate and the distribution of crossing over.
Lucía Del Priore, María Inés Pigozzi
doaj +1 more source
Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad +102 more
core +2 more sources
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae [PDF]
Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval-shaped human pathogen Streptococcus pneumoniae, efficiently segregate their chromosomes is poorly understood.
Avery +61 more
core +4 more sources
The Number of Meiotic Double-Strand Breaks Influences Crossover Distribution in Arabidopsis[OPEN]
Analysis of a spo11-1 hypomorphic allele in Arabidopsis showed that reducing the number of meiotic DSBs resulted in a profound redistribution of meiotic crossovers on a genome-wide scale.
Ming Xue +7 more
semanticscholar +1 more source

