Results 31 to 40 of about 855,599 (268)

An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans

open access: yesCell Reports, 2018
Summary: Balancer chromosomes are critical tools for genetic research. In C. elegans, reciprocal translocations that lead to aneuploidy have been widely used to maintain lethal and sterile mutations in stable stocks.
Katsufumi Dejima   +6 more
doaj   +1 more source

A universal method for automated gene mapping [PDF]

open access: yes, 2005
Small insertions or deletions (InDels) constitute a ubiquituous class of sequence polymorphisms found in eukaryotic genomes. Here, we present an automated high-throughput genotyping method that relies on the detection of fragment-length polymorphisms ...
Basler, Konrad   +6 more
core   +2 more sources

Crossing over...Markov meets Mendel. [PDF]

open access: yesPLoS Computational Biology, 2012
Chromosomal crossover is a biological mechanism to combine parental traits. It is perhaps the first mechanism ever taught in any introductory biology class.
Saad Mneimneh
doaj   +1 more source

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. [PDF]

open access: yes, 2011
Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones.
Cartman, ST   +6 more
core   +5 more sources

Manipulation of crossover frequency and distribution for plant breeding

open access: yesTheoretical and Applied Genetics, 2018
The crossovers (COs) that occur during meiotic recombination lead to genetic diversity upon which natural and artificial selection can act. The potential of tinkering with the mechanisms of meiotic recombination to increase the amount of genetic ...
A. Blary, E. Jenczewski
semanticscholar   +1 more source

The genomics of speciation in Drosophila: diversity, divergence, and introgression estimated using low-coverage genome sequencing.

open access: yesPLoS Genetics, 2009
In nature, closely related species may hybridize while still retaining their distinctive identities. Chromosomal regions that experience reduced recombination in hybrids, such as within inversions, have been hypothesized to contribute to the maintenance ...
Rob J Kulathinal   +2 more
doaj   +1 more source

Broad-scale recombination pattern in the primitive bird Rhea americana (Ratites, Palaeognathae). [PDF]

open access: yesPLoS ONE, 2017
Birds have genomic and chromosomal features that make them an attractive group to analyze the evolution of recombination rate and the distribution of crossing over.
Lucía Del Priore, María Inés Pigozzi
doaj   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

open access: yes, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad   +102 more
core   +2 more sources

SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae [PDF]

open access: yes, 2011
Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval-shaped human pathogen Streptococcus pneumoniae, efficiently segregate their chromosomes is poorly understood.
Avery   +61 more
core   +4 more sources

The Number of Meiotic Double-Strand Breaks Influences Crossover Distribution in Arabidopsis[OPEN]

open access: yesThe Plant Cell, 2018
Analysis of a spo11-1 hypomorphic allele in Arabidopsis showed that reducing the number of meiotic DSBs resulted in a profound redistribution of meiotic crossovers on a genome-wide scale.
Ming Xue   +7 more
semanticscholar   +1 more source

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