PLoS Genetics, 2009 In nature, closely related species may hybridize while still retaining their distinctive identities. Chromosomal regions that experience reduced recombination in hybrids, such as within inversions, have been hypothesized to contribute to the maintenance ...
Rob J Kulathinal +2 more
doaj +1 more source
Broad-scale recombination pattern in the primitive bird Rhea americana (Ratites, Palaeognathae). [PDF]
PLoS ONE, 2017 Birds have genomic and chromosomal features that make them an attractive group to analyze the evolution of recombination rate and the distribution of crossing over.
Lucía Del Priore, María Inés Pigozzi
doaj +1 more source
Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR) [PDF]
, 2013 During meiosis, formation and repair of programmed DNA double-strand breaks (DSBs) create genetic exchange between homologous chromosomes-a process that is critical for reductional meiotic chromosome segregation and the production of genetically diverse ...
Allison, Rachal M +4 more
core +1 more source
PLoS Genetics, 2008 During meiosis in most sexually reproducing organisms, recombination forms crossovers between homologous maternal and paternal chromosomes and thereby promotes proper chromosome segregation at the first meiotic division. The number and distribution of crossovers are tightly controlled, but the factors that contribute to this control are poorly ...
BARCHI, MARCO +5 more
+13 more sources
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae [PDF]
, 2011 Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval-shaped human pathogen Streptococcus pneumoniae, efficiently segregate their chromosomes is poorly understood.
Avery +61 more
core +5 more sources
Deciphering complex genome rearrangements in C. elegans using short-read whole genome sequencing
Scientific Reports, 2021 Genomic rearrangements cause congenital disorders, cancer, and complex diseases in human. Yet, they are still understudied in rare diseases because their detection is challenging, despite the advent of whole genome sequencing (WGS) technologies.
Tatiana Maroilley +5 more
doaj +1 more source
Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one [PDF]
, 2007 Background The vast majority of oocytes formed in the fetal ovary do not survive beyond birth. Possible reasons for their loss include the elimination of non-viable genetic constitutions arising through meiosis, however, the ...
Ghafari , Fataneh +2 more
core +4 more sources
Human imprinted chromosomal regions are historical hot-spots of recombination. [PDF]
PLoS Genetics, 2006 Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as well as on crossover position.
Ionel Sandovici +5 more
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The Overlap between Headache and Epilepsy in the Light of Recent Advances in Medical Genetics [PDF]
, 2014 Not ...
A. Ferretti +2 more
core +1 more source
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells.
PLoS ONE, 2019 When loss of heterozygosity (LOH) is correlated with loss or gain of a disease phenotype, it is often necessary to identify which gene or genes are involved.
Yasuhide Yoshimura +4 more
doaj +1 more source