Results 61 to 70 of about 855,599 (268)
A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. [PDF]
, 2019 The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Caballero, Iracema +10 more
core +4 more sources
bioRxiv, 2015 Meiotic recombination initiated by programmed double-strand breaks (DSBs) yields two types of interhomolog recombination products, crossovers and noncrossovers, but what determines whether a DSB will yield a crossover or noncrossover is not understood ...
Esther de Boer, M. Jasin, S. Keeney
semanticscholar +1 more source
Dynamics of male meiotic recombination frequency during plant development using Fluorescent Tagged Lines in Arabidopsis thaliana [PDF]
, 2017 Meiotic homologous recombination plays a central role in creating genetic variability, making it an essential biological process relevant to evolution and crop breeding.
De Storme, Nico, Geelen, Danny, Li, Fan
core +1 more source
Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
Advanced Science, EarlyView.To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source
Reconstitution of recombination-associated DNA synthesis with human proteins. [PDF]
, 2013 The repair of DNA breaks by homologous recombination is a high-fidelity process, necessary for the maintenance of genome integrity. Thus, DNA synthesis associated with recombinational repair must be largely error-free.
Grossi, Sara M +4 more
core +1 more source
Arabidopsis meiotic crossover hotspots overlap with H2A.Z nucleosomes at gene promoters
Nature Genetics, 2013 PRDM9 directs human meiotic crossover hot spots to intergenic sequence motifs, whereas budding yeast hot spots overlap regions of low nucleosome density (LND) in gene promoters.
Kyuha Choi +12 more
semanticscholar +1 more source
The polyploid continuum and the landscape of polyploid genomic variation
American Journal of Botany, EarlyView.Abstract Polyploid research has traditionally distinguished between autopolyploids and allopolyploids on the basis of evolutionary origins, modes of inheritance, or chromosomal pairing behavior during meiosis. It has long been recognized, however, that a binary classification does not accurately reflect the complexity and diversity inherent to ...
Alex D. Twyford +6 more
wiley +1 more source
Redistribution of Meiotic Crossovers Along Wheat Chromosomes by Virus-Induced Gene Silencing
Frontiers in Plant Science, 2021 Meiotic recombination is the main driver of genetic diversity in wheat breeding. The rate and location of crossover (CO) events are regulated by genetic and epigenetic factors.
Amir Raz +5 more
doaj +1 more source
PLoS Genetics, 2013 Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of recombination, provide the physical link that holds the homologs together as a pair, facilitating ...
M. F. Guiraldelli +4 more
semanticscholar +1 more source
Biotechnology and Bioengineering, EarlyView.Synthesis of amoxicillin: The reaction catalyzed by penicillin G acylase is investigated in an enzymatic reactor, considering both Michaelis–Menten and mechanism‐based models with reaction and equilibrium constants. Parameters are estimated via MCMC and Genetic Algorithm, with MCMC showing superior performance in validating the mathematical model in a ...
Lucas Figueiredo Formigosa +5 more
wiley +1 more source