Results 71 to 80 of about 33,239 (264)

Pch2 Links Chromosome Axis Remodeling at Future Crossover Sites and Crossover Distribution during Yeast Meiosis

open access: yesPLoS Genetics, 2009
Segregation of homologous chromosomes during meiosis I depends on appropriately positioned crossovers/chiasmata. Crossover assurance ensures at least one crossover per homolog pair, while interference reduces double crossovers. Here, we have investigated the interplay between chromosome axis morphogenesis and non-random crossover placement.
Neeraj Joshi   +3 more
openaire   +4 more sources

Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division [PDF]

open access: yes, 2014
Bacterial cell division is a fundamental process that requires the coordinated actions of a number of proteins which form a complex macromolecular machine known as the divisome.
Bottomley, Amy L.   +5 more
core   +1 more source

Genome editing using a versatile vector-based CRISPR/Cas9 system in Fusarium species

open access: yesScientific Reports, 2022
Fusarium species include important filamentous fungal pathogens that can infect plants, animals, and humans. Meanwhile, some nonpathogenic Fusarium species are promising biocontrol agents against plant pathogens.
Sota Shinkado   +6 more
doaj   +1 more source

Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains

open access: yeseLife, 2022
Cohesin organizes the genome by forming intra-chromosomal loops and inter-sister chromatid linkages. During gamete formation by meiosis, chromosomes are reshaped to support crossover recombination and two consecutive rounds of chromosome segregation ...
Rachael E Barton   +3 more
doaj   +1 more source

Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes

open access: yeseLife, 2014
We show that multiple, functionally specialized cohesin complexes mediate the establishment and two-step release of sister chromatid cohesion that underlies the production of haploid gametes. In C.
Aaron F Severson, Barbara J Meyer
doaj   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

open access: yesAdvanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu   +13 more
wiley   +1 more source

Patterns of Inter-Chromosomal Gene Conversion on the Male-Specific Region of the Human Y Chromosome [PDF]

open access: yes, 2017
The male-specific region of the human Y chromosome (MSY) is characterized by the lack of meiotic recombination and it has long been considered an evolutionary independent region of the human genome.
Cruciani, Fulvio   +2 more
core   +1 more source

AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance

open access: yesAdvanced Science, EarlyView.
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi   +8 more
wiley   +1 more source

A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. [PDF]

open access: yes, 2019
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Caballero, Iracema   +10 more
core   +4 more sources

Optisense: Computational Optimization for Strain Sensor Placement in Wearable Motion Tracking Systems

open access: yesAdvanced Intelligent Systems, EarlyView.
A computational framework for optimizing strain sensor placement in wearable motion tracking systems is presented. By combining dense strain mapping with a genetic algorithm, the method discovers counterintuitive yet highly effective configurations that reduce joint angle error by 32%.
Minu Kim   +4 more
wiley   +1 more source

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