How to halve ploidy : lessons from budding yeast meiosis [PDF]
, 2012 Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash +2 more
core +1 more source
Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation
Med Research, EarlyView.Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin +4 more
wiley +1 more source
Divergence of gene regulation through chromosomal rearrangements
BMC Genomics, 2010 Background The molecular mechanisms that modify genome structures to give birth and death to alleles are still not well understood. To investigate the causative chromosomal rearrangements, we took advantage of the allelic diversity of the duplicated p1 ...
Messing Joachim, Goettel Wolfgang
doaj +1 more source
Chromosome-Wide Characterization of Intragenic Crossover in Shiitake Mushroom, Lentinula edodes [PDF]
, 2021 Wenbing Gong +4 more
openalex +1 more source
Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae. [PDF]
, 2019 Saccharomyces cerevisiae Srs2, in addition to its well-documented antirecombination activity, has been proposed to play a role in promoting synthesis-dependent strand annealing (SDSA).
Ede, Christopher +8 more
core
Using genetic algorithms with grammar encoding to generate neural networks [PDF]
, 1995 Kitano's approach to neural network design is extended in the sense that not just the neural network structure, but also the values of the weights are coded in the chromosome.
Jain, L.C., Veelenturf, L.P.J., Vonk, E.
core +2 more sources
Functional synergy and genomic linkage of glyphosate resistance traits in Canada fleabane
Pest Management Science, EarlyView.Stacking target‐site and non‐target‐site glyphosate resistance mechanisms in Conyza canadensis results in strong synergistic effects. This study quantifies gene × gene interactions and maps linked resistance loci, advancing our understanding of herbicide resistance genetics and informing management strategies.
Eric R Page +4 more
wiley +1 more source
Identification of DNA motifs implicated in maintenance of bacterial core genomes by predictive modeling. [PDF]
PLoS Genetics, 2007 Bacterial biodiversity at the species level, in terms of gene acquisition or loss, is so immense that it raises the question of how essential chromosomal regions are spared from uncontrolled rearrangements.
David Halpern +6 more
doaj +1 more source
A CRISPR-induced DNA break can trigger crossover, chromosomal loss and chromothripsis-like rearrangements [PDF]
, 2023 Aviva Samach +8 more
openalex +1 more source
Sustainable Development, EarlyView.ABSTRACT Environmental awareness and sustainable transportation are critical in addressing climate change and urbanization. This research enhances understanding of environmental awareness through advanced machine learning (ML), focusing on cycling as a key component of sustainable urban mobility.
Mihrimah Özmen
wiley +1 more source