Results 11 to 20 of about 22,195,386 (187)

“Something Extra on Chromosome 5”: Parents’ Understanding of Positive Prenatal Chromosomal Microarray Analysis (CMA) Results [PDF]

Journal of Genetic Counseling, 2016
AbstractThis study aims to explore how couples’ understanding of the nature and consequences of positive prenatal chromosomal microarray analysis (CMA) results impacts decision‐making and concern about pregnancy. We interviewed 28 women and 12 male partners after receiving positive results and analyzed the transcripts to assess their understanding and ...
Barbara A Bernhardt, Ronald J Wapner, Allison Werner-Lin   +2 more
exaly   +5 more sources

The chromosomal microarray analysis (CMA) used for examination of products of conception

Gynecological Endocrinology, 2020
Chromosomal aberrations in the product of conceptions (POC) are detected in around 50% lost pregnancies. Karyotype analysis of the POC, limited by high failure rate of culture, is not always carried out.
Kanivets I., Korostelev S., Totchiev G., Pyankov D., Gnetetskaya V.   +4 more
core   +5 more sources

Genetic counseling for a prenatal diagnosis of structural chromosomal abnormality with high-resolution analysis using a single nucleotide polymorphism microarray

Clinics and Practice, 2016
A 41-year old pregnant woman underwent amniocentesis to conduct a conventional karyotyping analysis; the analysis reported an abnormal karyotype: 46,XY,add(9)(p24). Chromosomal microarray analysis (CMA) is utilized in prenatal diagnoses.
Akiko Takashima, Naoki Takeshita, Toshihiko Kinoshita   +2 more
doaj   +2 more sources

Potentials and challenges of chromosomal microarray analysis in prenatal diagnosis [PDF]

Frontiers in Genetics, 2022
Introduction: For decades, conventional karyotyping analysis has been the gold standard for detecting chromosomal abnormalities during prenatal diagnosis.
Xijing Liu, Xijing Liu, Xijing Liu, Shanling Liu, Shanling Liu, Shanling Liu, He Wang, He Wang, He Wang, Ting Hu, Ting Hu, Ting Hu   +11 more
doaj   +2 more sources

Prenatal genetic diagnosis associated with fetal ventricular septal defect: an assessment based on chromosomal microarray analysis and exome sequencing [PDF]

Frontiers in Genetics, 2023
Objective: In the study, we investigated the genetic etiology of the ventricular septal defect (VSD) and comprehensively evaluated the diagnosis rate of prenatal chromosomal microarray analysis (CMA) and exome sequencing (ES) for VSD to provide evidence ...
You Wang, You Wang, Ru Li, Fang Fu, Ruibin Huang, Dongzhi Li, Can Liao, Can Liao   +7 more
doaj   +2 more sources

Additional information from chromosomal microarray analysis (CMA) over conventional karyotyping when diagnosing chromosomal abnormalities in miscarriage:a systematic review and meta-analysis

BJOG: An International Journal of Obstetrics & Gynaecology, 2013
Approximately 50% of spontaneous miscarriages are associated with chromosome abnormalities. Identification of these karyotypic abnormalities helps to estimate recurrence risks in future pregnancies.
McMullan, D, Coomarasamy, A, Dhillon, Rima; id_orcid, Kilby, Mark, Morris, Rachel; id_orcid, Hillman, Sarah; id_orcid, Williams, D   +6 more
core   +3 more sources

Chromosomal Abnormalities Detected by Chromosomal Microarray Analysis and Karyotype in Fetuses with Ultrasound Abnormalities [PDF]

International Journal of General Medicine
Liubing Lan,1,2 Dandan Luo,1,2 Jianwen Lian,1 Lingna She,1,3 Bosen Zhang,1,3 Hua Zhong,1 Huaxian Wang,1 Heming Wu1 1Department of Prenatal Diagnostic Center, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Obstetrics ...
Lan L, Luo D, Lian J, She L, Zhang B, Zhong H, Wang H, Wu H   +7 more
doaj   +1 more source

Chromosomal microarray analysis for the prenatal diagnosis in fetuses with fetal echogenic bowel: a retrospective cohort study

BMC Pregnancy and Childbirth
Objective Fetal echogenic bowel (FEB) is often accompanied by the presence of chromosomal abnormalities. Here, we intend to evaluate the efficiency of chromosomal microarray analysis (CMA) for identifying fetal risks associated with FEB, with a focus on ...
Wenli Wu, Meng Tian, Miao Liu, Dongmei Man, Fengge Wang   +4 more
doaj   +2 more sources

A retrospective study for the diagnostic value of chromosomal microarray analysis in fetuses with high-risk prenatal indications [PDF]

Frontiers in Genetics
ObjectiveThe aim of this study was to determine the diagnostic value of prenatal chromosomal microarray analysis (CMA) for fetuses at high risk for various conditions on chromosomal abnormalities.MethodsIn the study, 8,560 clinical samples were collected
Hui Xiao, Junfang Xiao, Huan Zhang, Shuhui Huang, Qing Lu, Huizhen Yuan, Yongyi Zou, Bicheng Yang, Yanqiu Liu   +8 more
doaj   +2 more sources

Prenatal diagnosis and genetic counseling of an inherited Xq24q25 deletion associated with normal phenotype

Molecular Cytogenetics, 2022
Background Copy number variants (CNVs) are an important source of normal and pathogenic genome variations. CNVs identified in prenatal cases need careful considerations and correct interpretation if those are harmless or harmful variants from the norm ...
Yaqing Zhou, Mingxi Zhang, Yanmin Zhu, Qi Zhao   +3 more
doaj   +1 more source