Noninvasive prenatal testing (NIPT) results are less accurate the later applied during pregnancy
Taiwanese Journal of Obstetrics and GynecologyObjective: Noninvasive prenatal testing (NIPT) has been introduced in prenatal genetics, recently. Even though it is connected with biological, technical, medical and ethical issues also reviewed here, it is meanwhile applied as a standard screening test.
Thomas Liehr
exaly +6 more sources
Taiwanese Journal of Obstetrics and Gynecology, 2018 Objective: The coexistence of maternal malignancy and pregnancy has received increasing attention in Noninvasive prenatal testing (NIPT) studies. Malignancy in pregnant women potentially affects the copy number variation (CNV) profile in NIPT results ...
Xin Jin, Shu-Huei Shen, Mao Mao
exaly +4 more sources
Prenatal diagnosis of imprinted associated chromosome abnormalities identified by noninvasive prenatal testing (NIPT) [PDF]
Scientific ReportsTo explore the clinical value of noninvasive prenatal testing (NIPT) combined with chromosomal microarray analysis (CMA)/copy number variation sequencing (CNV-seq), methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA), and fluorescence in situ hybridization (FISH) in the early screening of imprinted chromosome abnormalities ...
Haishan Peng, Yaping Hou
exaly +5 more sources
One-step noninvasive prenatal testing (NIPT) for autosomal recessive homozygous point mutations using digital PCR. [PDF]
Sci Rep, 2018 AbstractPreviously, we introduced a noninvasive prenatal testing (NIPT) protocol for diagnosing compound heterozygous autosomal recessive point mutations via maternal plasma DNA and simulated control genomic DNA sampling based on fetal DNA fraction.
Chang MY +10 more
europepmc +5 more sources
Has Noninvasive Prenatal Testing (NIPT) Come of Age? [PDF]
J Obstet Gynaecol India, 2015 Recent advances in genomic sequencing and bioinformatics have led to the development of noninvasive detection methods with detection rates approaching those obtained with amniocentesis and chorionic villus sampling (CVS) [1, 2]. Recently, a novel prenatal testing method has become available. This method, known as noninvasive prenatal testing (NIPT), is
Allahbadia GN.
europepmc +4 more sources
Potential influence of parental copy number variations on noninvasive prenatal testing (NIPT): two case reports. [PDF]
Mol Cytogenet, 2020 Abstract Background Small subchromosomal deletions and duplications caused by copy number variants (CNVs) can now be detected with noninvasive prenatal testing (NIPT) technology. However, the clinical utility and validity of this screening for CNVs are still unknown.
Qi Y +6 more
europepmc +5 more sources
Cross-Sectional Survey of Obstetrical Providers’ Knowledge, Attitudes, and Use of Noninvasive Prenatal Testing for 22q11.2 Deletion [PDF]
American Journal of Perinatology ReportsObjective This study’s primary objective was to characterize obstetrical providers’ knowledge and utilization of noninvasive prenatal testing (NIPT) for 22q11.2 deletion screening.
Juliana Simon +4 more
doaj +2 more sources
Uptake of noninvasive prenatal testing (NIPT) in women following positive aneuploidy screening [PDF]
Prenatal Diagnosis, 2013 ABSTRACTObjectiveThe aim of this study was to investigate how the introduction of noninvasive prenatal testing (NIPT) impacted women's testing choices following a positive prenatal screening (PNS) result.MethodsBeginning in March 2012, women referred to our Prenatal Diagnosis Center following a positive PNS result were offered NIPT or invasive prenatal
Mary E Norton
exaly +3 more sources
Comparing the Introduction and Implementation of Noninvasive Prenatal Testing (NIPT) in Japan, the Netherlands, and the United States: An Integrative Review. [PDF]
Prenat DiagnABSTRACTPrevious studies suggest that NIPT's implementation differed widely across countries but offer limited insight into what shaped these differences. To address this gap, we conducted an in‐depth analysis of how NIPT was incorporated into prenatal care in the US, the Netherlands, and Japan—countries with similar economic status—to identify ...
Connor C +7 more
europepmc +4 more sources
Comments on Editorial: Has Noninvasive Prenatal Testing (NIPT) Come of Age? [PDF]
J Obstet Gynaecol India, 2017 Singh C, Kaul A.
europepmc +4 more sources