Results 1 to 10 of about 518 (105)

A Comprehensive Review of the Genetic Etiology and Management of Orofacial Clefts

Pediatric Discovery, EarlyView.
ABSTRACT Cleft lip (CL) and cleft palate (CP), collectively referred to as orofacial clefts (OFCs), are among the most common birth defects and can have significant effects on speech, nutrition, and physical and psychosocial development. Manifestation, classification, and treatment plans of OFCs are diverse and not standardized.
Emily Kim, Rebeka Dejenie, Caroline Kim, Russell Reid   +3 more
wiley   +1 more source

Ultrasound and SNP-based cell-free DNA zygosity testing in twin pregnancies

The Journal of Maternal-Fetal & Neonatal Medicine
Introduction The importance of prenatal determination of chorionicity for the management of twin pregnancies is well recognized. However, research on the contribution of prenatal evaluation of zygosity to the management of twins is limited.
Ruben Quintero, K. Joseph Hurt, Neeta L. Vora, Neil S. Seligman, Gerard P. Reilly, Myra J. Wick, Samuel B. Wolf, Maeve Hopkins, Thomas Westover, Homa K. Ahmadzia, Camille Kanaan, Andrei Rebarber, Eftichia V. Kontopoulos, Jingwen Zhang, Melissa Egbert, Sophia Vourthis, Ashley Cantu-Weinstein, Jessica L. Saben, Russ Jelsema, Vivienne Souter, Clark T. Johnson, Peter Benn   +21 more
doaj   +1 more source

Application value of NIPT for uncommon fetal chromosomal abnormalities

Molecular Cytogenetics, 2020
Objective To investigate the clinical value of noninvasive prenatal testing (NIPT) for fetal chromosomal deletion, duplication, and sex chromosome abnormalities.
Lianli Yin, Yinghua Tang, Qing Lu, Aiping Pan, Mingfang Shi   +4 more
doaj   +1 more source

Female pelvic floor protection—Where do we have to go?

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Long lasting improvement of women's health needs that all professions involved in pregnancy, birth, postpartum rehabilitation and diagnostics and treatment of pelvic floor disorders gather together to increase pelvic floor protection. Abstract Pelvic floor protection has a growing awareness and importance in long lasting strategies to provide female ...
Miriam Deniz, Luisa Wirth, Kathrin Beilecke, Ralf Tunn, Markus Huebner   +4 more
wiley   +1 more source

Early noninvasive prenatal paternity testing by targeted fetal DNA analysis

Scientific Reports, 2023
Today the challenge in paternity testing is to provide an accurate noninvasive assay that can be performed early during pregnancy. This requires the use of novel analytical methods capable of detecting the low fraction of circulating fetal DNA in ...
Géraldine Damour, Karine Baumer, Hélène Legardeur, Diana Hall   +3 more
doaj   +1 more source

Salivary uric acid remote serial self‐testing for prediction of adverse pregnancy outcomes of uteroplacental dysfunction

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Remote, weekly self‐testing of salivary uric acid enables longitudinal monitoring throughout pregnancy. RGB‐derived measurements are combined with maternal characteristics in a model using 4 weeks of prior data. This approach provides individualized prediction of hypertensive disorders of pregnancy and fetal growth restriction within 1 week.
Basia Chmielewska, Chao Wang, Nick Macklon, Amar Bhide, Basky Thilaganathan   +4 more
wiley   +1 more source

Noninvasive screening tools for Down syndrome: a review

International Journal of Women's Health, 2013
Meagan Smith, Jeannie Visootsak Emory University, Department of Human Genetics, Atlanta, GA, USA Abstract: Down syndrome is the leading cause of prenatal chromosome abnormalities, accounting for 53% of all reported chromosome conditions.
Smith M, Visootsak J
doaj  

Amniotic fluid karyotype analysis and prenatal diagnosis strategy of 3117 pregnant women with amniocentesis indication

Journal of Comparative Effectiveness Research, 2023
Aim: To examine prenatal diagnosis strategies through fetal karyotype analysis for 3117 pregnant women with genetic amniocentesis indications. Materials & methods: According to the different indications for amniocentesis, the study was divided into 8 ...
Yi Liu, Xue-Cheng Sun, Guo-Jian Lv, Ji-Hong Liu, Chen Sun, Kai Mu   +5 more
doaj   +1 more source

Budesonide and Surfactant Therapy Versus Surfactant Alone on Incidence of Lung Disease in Preterm Infants (BEST Lung): Study Protocol for a Systematic Review and Individual Participant Data Meta‐Analysis With Nested Prospective Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Introduction Bronchopulmonary dysplasia (BPD) is a leading cause of morbidity and mortality in preterm infants. Combining surfactant with budesonide has been proposed to prevent BPD, but results from existing randomised controlled trials (RCTs) are conflicting.
James X. Sotiropoulos, Brett J. Manley, Sol Libesman, Namasivayam Ambalavanan, Abhik Das, Christopher J. D. Mckinlay, Nalinikanta Panigrahy, Melinda Cruz, David Nguyen, Jonathan Williams, Peter Davis, Kylie E. Hunter, Anna Lene Seidler   +12 more
wiley   +1 more source

Non-Invasive Prenatal Testing (NIPT): A Paradigm Shift in Prenatal Care

International Journal of Preventive Medicine
Prenatal screening has undergone a profound transformation with the emergence of Non-Invasive Prenatal Testing (NIPT), a technology that analyzes cell-free fetal DNA (cffDNA) in maternal blood to detect common chromosomal abnormalities.
Ram K. Garg, Yogesh Kumar, Ram Niwas, Jitendra Singh   +3 more
doaj   +1 more source