Results 1 to 10 of about 1,636,041 (314)

DNA damage responses in the context of the cell division cycle

, 2010
During my PhD, I have investigated aspects of the DNA damage response (DDR) in the context of three different cellular scenarios: DNA damage signalling in response to double-strand breaks during mitosis, coordination of DNA replication with DNA damage ...

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Increased plasma concentration of cell-free DNA precedes disease recurrence in children with high-risk neuroblastoma [PDF]

, 2020
Yan Su, Lijun Wang, Chiyi Jiang, Zhixia Yue, Hongjun Fan, Huimin Hong, Chao Duan, Mei Jin, Dawei Zhang, Lihua Qiu, Xianfeng Cheng, Zhong Xu, Xiaoli Ma   +12 more
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Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining.

, 2015
Deficiencies in DNA double-strand break (DSB) repair lead to genetic instability, a recognized cause of cancer initiation and evolution. We report that the retinoblastoma tumor suppressor protein (RB1) is required for DNA DSB repair by canonical non ...
Spanswick, VJ, Maciej T. Luczynski, Rieger, Simone, Luczynski, Maciej T., Cook, Rebecca, Cook, R, Hartley, JA, Paul H. Huang, Victoria J. Spanswick, Huang, Paul H., Hartley, John A., John A. Hartley, Luczynski, MT, Rieger, S, Mittnacht, Sibylle, Mittnacht, S, Spanswick, Victoria J., Moquet, J, Huang, PH, Kai Rothkamm, Zoumpoulidou, Georgia, Jayne Moquet, Zoumpoulidou, G, Georgia Zoumpoulidou, Simone Rieger, Sibylle Mittnacht, Rothkamm, K, Rebecca Cook, Moquet, Jayne, Rothkamm, Kai   +29 more
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DNA packaging and polycation length determine DNA susceptibility to free radical damage in condensed DNA

, 2023
In nature, DNA exists primarily in a highly compacted form. The compaction of DNA in vivo is mediated by cationic proteins; histone in somatic nuclei and protamines in sperm chromatin.
Daniel, Kirchhoff, Ehigbai, Oikeh, Yongmei, Wang, Jason, DeRouchey, Jesse, Ziebarth   +4 more
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What will be the role of first-trimester ultrasound if cell-free DNA screening for aneuploidy becomes routine? [PDF]

, 2014
Jiri Sonek, Howard Cuckle
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5-Hydroxymethylcytosine Signatures in Circulating Cell-Free DNA as Diagnostic Biomarkers for Late-Onset Alzheimer’s Disease [PDF]

, 2021
Lei Chen, Shunliang Xu, Qianqian Shen, Hongzhuan Yu, Shengjie Pei, Yangting Zhang, Xin He, Qiuzhen Wang, Duo Li   +8 more
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Interspecies somatic cell nuclear transfer is dependent on compatible mitochondrial DNA and reprogramming factors [PDF]

, 2011
Interspecies somatic cell nuclear transfer (iSCNT) involves the transfer of a nucleus or cell from one species into the cytoplasm of an enucleated oocyte from another.
St. John Justin C., Dickinson Adam, Daniel A Mitchell, Yan Jiang, Kelly Richard, Peters Amy, Fulka, Helena, Helena Fulka, Justin C. St. John, Dickinson, Adam, St. John, Justin C., Adam Dickinson, Daniel A. Mitchell, Justin C St John, Jiang Yan, Fulka Helena, Kelly, Richard D. W., Mitchell Daniel A., Mitchell, Daniel A., Peters, Amy, Richard Kelly, Jiang, Yan, Amy Peters   +22 more
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Cell Free DNA and Genometastasis

Experimed, 2019
Cell free DNAs (cfDNA) are short DNA fragments which are present in all biological fluids and cell culture medium. They were first detected in blood plasma by Mandel and Metais in 1948. cfDNAs are mostly endogenous-derived fragments that are determined in lipid/protein rich complexes or particles with membranes.
KOÇANA, Cemal Çağıl, TOPRAK, Selin, YAŞA, Büşra, HEKİMOĞLU, Hilal, TOKDEMİR, Selçuk Sözer   +4 more
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Optical Nanosensor Architecture for Cell-Signaling Molecules Using DNA Aptamer-Coated Carbon Nanotubes

, 2011
We report a novel optical biosensor platform using near-infrared fluorescent single-walled carbon nanotubes (SWNTs) functionalized with target-recognizing aptamer DNA for noninvasively detecting cell-signaling molecules In real time.
Rickus, Jenna, Jong Hyun Choi, Choi, Jong Hyun, Sauffer, M. Dane, Benjamin A. Baker, Salgado, Janette, Jaroch, David, Janette Salgado, D. Marshall Porterfield, M. Dane Sauffer, David Jaroch, Jenna L. Rickus, Cha, Tae-Gon, Tae-Gon Cha, Baker, Benjamin A., Porterfield, D. Marshall   +15 more
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OC11.05: Effectiveness and decrease in invasive testing using cell‐free DNA contingent screening in a single institution [PDF]

, 2020
A.M. Cubo Nava, M. Rodríguez Martín, C. Martín Seisdedos, T. Costas Rodríguez, F. Goenaga Sánchez, V. Lapresa Alcalde, M. Huélamo Moruno, M. Rodrigo Caro   +7 more
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