Results 21 to 30 of about 12,684,378 (242)
Tumor Biology, 2017 Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar +7 more
doaj +1 more source
Circulating biomarkers to monitor cancer progression and treatment
Computational and Structural Biotechnology Journal, 2016 Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still, the standard diagnostic approach relies on the analysis of a single tumor sample from a local or metastatic site that is obtained at a given time point. Due to
Suthee Rapisuwon +2 more
doaj +1 more source
Comparison of methods for the quantification of cell-free DNA isolated from cell culture supernatant
Tumor Biology, 2019 Gaining a better understanding of the biological properties of cell-free DNA constitutes an important step in the development of clinically meaningful cell-free DNA–based tests.
Abel Jacobus Bronkhorst +2 more
doaj +1 more source
Study the Role of Cell Free DNA in the Diagnosis of Hepatocellular Carcinoma, an Egyptian Study
Asian Pacific Journal of Cancer Biology, 2022 Background and objective: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Since the conventional tissue biopsy and AFP have limited value, a new promising diagnostic method” liquid biopsy” has emerged.
Noha Hassan Radwan +3 more
doaj +1 more source
Noninvasive prenatal diagnosis of fetal RhD status using cell-free fetal DNA in maternal plasma with TaqMan® real-time PCR assay [PDF]
, 2007 Prenatal diagnosis is now part of established obstetric practice in many countries. However, conventional methods of prenatal diagnosis of obtaining fetal tissues for genetic analysis, including amniocentesis and chorionic villus sampling, are invasive
Rekhviashvili, Tea
core +1 more source
Biochemical and clinical diagnostic aspects of circulating nucleic acids [PDF]
, 2005 We investigated the size distribution of fetal DNA using a combination of agorose gel electrophoresis, Southern blot and real time PCR assay. Our results showed plasma DNA presents apoptotic characteristics and the cell free fetal DNA is generally ...
Li, Ying
core +1 more source
Practical Laboratory Medicine, 2019 Objectives: To compare the Roche Cell-Free DNA Collection Tubes® against the Streck Cell-Free DNA BCT®s for sample stability using Cell Free DNA (cfDNA) from healthy volunteers (n = 20).
Sarah Parackal +4 more
doaj +1 more source
PLoS ONE, 2022 High-level amplification of MDM2 and other genes in the 12q13-15 locus is a hallmark genetic feature of well-differentiated and dedifferentiated liposarcomas (WDLPS and DDLPS, respectively).
Joanna Przybyl +8 more
doaj +3 more sources
The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts [PDF]
, 1991 The sites of nascent DNA synthesis were compared with the distribution of the proliferating cell nuclear antigen (PCNA) in S-phase nuclei of human diploid fibroblasts (HDF) by two in vitro techniques.
Kill, IR +4 more
core +4 more sources
Cell-free DNA testing: future applications in gastroenterology and hepatology
Therapeutic Advances in Gastroenterology, 2019 The application of next-generation sequencing in clinical practice is increasing as accuracy and interpretation have improved and the cost continues to decline rapidly.
Inuk Zandvakili +1 more
doaj +1 more source