Results 151 to 160 of about 267,700 (194)

Engineering chromosomal rearrangements in mice

Nature Reviews Genetics, 2001
The combination of gene-targeting techniques in mouse embryonic stem cells and the Cre/loxP site-specific recombination system has resulted in the emergence of chromosomal-engineering technology in mice. This advance has opened up new opportunities for modelling human diseases that are associated with chromosomal rearrangements.
Y, Yu, A, Bradley
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A mathematical theory of chromosomal rearrangements

Journal of Genetics, 1947
A theory is given of the process of chromosomal structural rearrangement following irradiation. The theory applies to nuclei in which the union of breakage ends is at random, and assumes that the number of breaks primarily produced is proportional to the dose.
J B S, HALDANE, D E, LEA
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Chromosome rearrangements in Giardia lamblia

Parasitology Today, 1994
Recent studies have shown that the genome of Giardia lamblia is plastic. Clinical isolates exhibit extensive karyotypic heterogeneity and chromosome rearrangements occur frequently, in vitro. In this review, Sylvie Le Blancq looks at genome organization and the impact of DNA rearrangement events.
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Multiple chromosome rearrangements in a fibrosarcoma

Cancer Genetics and Cytogenetics, 1996
Clonal chromosome changes of a complex nature were found in a case of adult fibrosarcoma. Few studies on this tumor have been published, all showing complex changes without characteristic anomalies.
P, Dal Cin, P, Pauwels, R, Sciot, H, Van den Berghe   +3 more
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Genome Rearrangements with Partially Ordered Chromosomes

Journal of Combinatorial Optimization, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chunfang Zheng, David Sankoff
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What Is a Complex Chromosome Rearrangement?

American Journal of Medical Genetics Part A, 2013
No single definition of a complex chromosome rearrangement (CCR) can adequately cover the whole range of possible structural rearrangements. There are highly complex CCRs with multiple breaks that involve three, four or more chromosomes, but there are also CCRs that involve just two chromosomes or even a single chromosome.
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Chromosomal Rearrangements and Mental Retardation

Pediatric Research, 2000
A review of: Knight SJL, Regan R, Nicod A, et al. 1999 Subtle Chromosomal Rearrangements in Children with Unexplained Mental Retardation. Lancet 354:1676–1681.
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Mechanisms of Chromosome Rearrangements

2012
The striking diversity of land plants is associated with immense genetic variation manifested also by a wide range of genome sizes and chromosome numbers. Nuclear genome size across land plants varies more than 2,300-fold from ~64 Mb (Genlisea aurea; Greilhuber et al. 2006) to ~150,000 Mb (Paris japonica; Pellicer et al. 2010).
Martin A. Lysák, Ingo Schubert
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Chromosomal rearrangements and speciation

Trends in Microbiology, 2000
Reproductive isolation in the Saccharomyces genus is the result of post-zygotic barriers, as many species mate successfully but the hybrids are sterile. To test whether chromosomal rearrangements were the cause of reproductive isolation (and therefore speciation) in yeast, Fischer et al.1xChromosomal evolution in Saccharomyces. Fischer, G.
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Quantitative Evaluation of Chromosomal Rearrangements in Gene-Edited Human Stem Cells by CAST-Seq

Cell Stem Cell, 2021
Julia Klermund, Giandomenico Turchiano, Melanie Boerries   +2 more
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