Results 251 to 260 of about 158,249 (312)
The FEBS Journal, EarlyView.The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao +3 more
wiley +1 more source
Exploring the Role of Environmental Factors on Chromosomal Translocations Associated With Childhood Leukaemia. [PDF]
Cancer MedSaville JR +3 more
europepmc +1 more source
Characterization of Acute Myeloid Leukemia With t(16;21) Translocation: Cytogenetic, Molecular, and Immunophenotypic Findings. [PDF]
World J OncolBravo-Davila M +3 more
europepmc +1 more source
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1997
Abstract To generate chromosomal translocations in ES cells using the Cre/loxP system two consecutive homologous recombination events are necessary. In the first step, a positive selection marker gene with one loxP site (e.g. loxP-neo) must be introduced by homologous recombination on one chromosome and a second selection marker with ...
Raul M Torres, Ralf Kühn
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Abstract To generate chromosomal translocations in ES cells using the Cre/loxP system two consecutive homologous recombination events are necessary. In the first step, a positive selection marker gene with one loxP site (e.g. loxP-neo) must be introduced by homologous recombination on one chromosome and a second selection marker with ...
Raul M Torres, Ralf Kühn
openaire +1 more source
Chromosomal translocations and sarcomas
Current Opinion in Oncology, 2002This review examines how the identification of tumor-specific translocations and fusion proteins has advanced the basic scientific and clinical understanding of sarcomas. Recent genetic advances, including the ASPL-TFE3 fusion of alveolar soft part sarcoma, the JAZF1-JJAZ1 fusion of endometrial stromal sarcoma, and HMGIC fusions in liposarcoma, are ...
Jeannette L, Bennicelli +1 more
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PHILADELPHIA CHROMOSOME BY TRANSLOCATION
The Lancet, 1973SCOPUS: le.j ; info:eu-repo/semantics ...
Petit, Paul, Cauchie, Charles
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Chromosomal translocations in cancer
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2008Genetic alterations in DNA can lead to cancer when it is present in proto-oncogenes, tumor suppressor genes, DNA repair genes etc. Examples of such alterations include deletions, inversions and chromosomal translocations. Among these rearrangements chromosomal translocations are considered as the primary cause for many cancers including lymphoma ...
Nambiar, Mridula +2 more
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Mechanisms of oncogenic chromosomal translocations
Annals of the New York Academy of Sciences, 2014Chromosome translocations are caused by inappropriate religation of two DNA double‐strand breaks (DSBs) in heterologous chromosomes. These DSBs can be generated by endogenous or exogenous sources. Endogenous sources of DSBs leading to translocations include inappropriate recombination activating gene (RAG) or activation‐induced deaminase (AID) activity
Michael, Byrne +7 more
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Chromosome Translocation in Peripheral Neuroepithelioma
New England Journal of Medicine, 1984PERIPHERAL neuroepithelioma (peripheral neuroblastoma) is an uncommon malignant tumor of the peripheral nervous system with a histologic appearance similar to that of classical childhood neuroblast...
J, Whang-Peng +5 more
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