Results 261 to 270 of about 158,249 (312)

Sex Chromosome Translocations

2018
Abstract The sex chromosomes (gonosomes) are different, and sex chromosome translocations need to be considered separately from translocations between autosomes. A sex chromosome can engage in translocation with an autosome, with the other sex chromosome, or even with its own homolog.
R. J McKinlay Gardner, David J Amor
openaire   +1 more source

Sex chromosome translocations and speciation

Nature, 1976
SPECIATION is the primary process of cladogenetic evolution. It is generally agreed that genetic divergence sufficient to produce reproductive isolation among populations is acquired in the allopatric state1–4. One of the major problems of evolutionary genetics is, then, characterisation of the genetic differences which actually produce the ...
M L, Tracey, S A, Espinet
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Sex Chromosome Translocations

2011
Abstract THE SEX CHROMOSOMES (gonosomes) are different, and sex chromosome translocations need to be considered separately from translocations between autosomes. A sex chromosome can engage in translocation with an autosome, with the other sex chromosome, or even with its homolog.
R. J. McKinlay Gardner, Grant R. Sutherland, Lisa G. Shaffer   +2 more
openaire   +1 more source

Translocation chromosome karyotypes of the Robertsonian translocation carriers' embryos

Fertility and Sterility, 2010
To explore the translocation karyotypes of the Robertsonian translocation (RT) carriers' embryos in their preimplantation genetic diagnosis (PGD) cycles.Retrospective.University-affiliated IVF center.A total of 35 RT carrier couples underwent 39 blastomere PGD cycles from August 2005 to June 2008.The PGD analysis of embryos.Meiotic segregation patterns
Huang, Jin, Liu, Ping, Qiao, Jie, Lian, Ying, Chen, Yongjian   +4 more
openaire   +2 more sources

Chromosome translocations: dangerous liaisons revisited

Nature Reviews Cancer, 2001
Although it has been clear for more than a century that the chromosomes in human tumour cells are often wildly abnormal, there has been controversy as to whether these changes are primary events or are merely secondary epiphenomena that reflect the genomic instability of these cells.
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Chromosomal translocations: revisited yet again

Blood, 2008
It is hard today, in 2008, when genetic changes in cancer and specifically hematologic malignancies are accepted as central players, to look back 50 years and realize how different the landscape was then.
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DNA Repair and Chromosomal Translocations

2015
The balance between DNA damage, especially double strand breaks, and DNA damage repair is a critical determinant of chromosomal translocation frequency. The non-homologous end-joining repair (NHEJ) pathways seem to play the major role in the generation of chromosomal translocations.
Stefan K, Bohlander, Purvi M, Kakadia
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Chromosomal translocations in human cancer

Nature, 1994
Chromosomal abnormalities in tumours were recognized at the end of the last century but their significance has only recently become clear. Distinct translocations in leukaemias and in solid tumours lead to the activation of proto-oncogene products or, more commonly, creation of tumour-specific fusion proteins.
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Chromosome translocations: Dangerous liaisons

Journal of Laboratory and Clinical Medicine, 1998
Many chromosome abnormalities, especially translocations or inversions, are closely associated with a particular morphologic or phenotypic subtype of leukemia, lymphoma, or sarcoma. Cloning the genes at the breakpoints of these rearrangements has provided critical tools for more-precise diagnosis; in some cases the particular diagnosis has prognostic ...
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
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