Results 11 to 20 of about 1,768,096 (341)

Targeting chromosome trisomy for chromosome editing [PDF]

open access: yesScientific Reports, 2021
AbstractA trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in chicken DT40 cells.
Kouji Hirota   +3 more
openaire   +4 more sources

Chromosomes, chromosome anomalies [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Educational Items on Chromosomes, chromosome anomalies.
Huret, JL, Leonard, C, Savage, JRK
openaire   +3 more sources

Chromosome Painting of Mouse Chromosomes [PDF]

open access: yes, 2018
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
openaire   +4 more sources

A Chromosome RNAissance [PDF]

open access: yesCell, 2002
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
Abby F. Dernburg, Gary H. Karpen
openaire   +2 more sources

Holocentric chromosomes

open access: yesPLOS Genetics, 2020
Holocentric chromosomes possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes [1]. They have been described for the first time in cytogenetic experiments dating from 1935 and, since this first observation, the term holocentric chromosome has referred to chromosomes that: i.
Mauro Mandrioli, Gian Carlo Manicardi
openaire   +6 more sources

The architecture of chicken chromosome territories changes during differentiation [PDF]

open access: yes, 2004
BACKGROUND: Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory.
Bonifer, C.   +7 more
core   +4 more sources

Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]

open access: yesThe Journal of cell biology, 1983
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C.   +1 more
openaire   +4 more sources

Chromosome Oscillations in Mitosis [PDF]

open access: yes, 2005
Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar   +8 more
core   +2 more sources

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]

open access: yes, 2015
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco   +9 more
core   +3 more sources

Physical mapping integrated with syntenic analysis to characterize the gene space of the long arm of wheat chromosome 1A [PDF]

open access: yes, 2013
Background: Bread wheat (Triticum aestivum L.) is one of the most important crops worldwide and its production faces pressing challenges, the solution of which demands genome information. However, the large, highly repetitive hexaploid wheat genome has
Akpınar, Bala Anı   +15 more
core   +5 more sources

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