Results 11 to 20 of about 1,311,035 (215)

The megabase-scale crossover landscape is largely independent of sequence divergence

open access: yesNature Communications, 2022
The frequency of recombination varies along chromosomes and highly correlates with sequence divergence. Here, the authors show that polymorphisms are not a major determinant of the megabase-scale recombination landscape in Arabidopsis, which is rather ...
Qichao Lian   +6 more
doaj   +1 more source

Chromosome Painting of Mouse Chromosomes [PDF]

open access: yes, 2018
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
openaire   +3 more sources

A Chromosome RNAissance [PDF]

open access: yesCell, 2002
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
Abby F. Dernburg, Gary H. Karpen
openaire   +2 more sources

Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model

open access: yesScientific Reports, 2023
Dystrophin maintains membrane integrity as a sarcolemmal protein. Dystrophin mutations lead to Duchenne muscular dystrophy, an X-linked recessive disorder.
Yosuke Hiramuki   +14 more
doaj   +1 more source

Holocentric chromosomes

open access: yesPLOS Genetics, 2020
Holocentric chromosomes possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes [1]. They have been described for the first time in cytogenetic experiments dating from 1935 and, since this first observation, the term holocentric chromosome has referred to chromosomes that: i.
Mauro Mandrioli, Gian Carlo Manicardi
openaire   +6 more sources

The architecture of chicken chromosome territories changes during differentiation [PDF]

open access: yes, 2004
BACKGROUND: Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory.
Bonifer, C.   +7 more
core   +4 more sources

Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting [PDF]

open access: yesGenetics Selection Evolution, 2003
A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection. For the porcine inversion, probes specific for p arms and q arms were produced and hybridised simultaneously on metaphases of a heterozygote ...
Pinton, Alain   +2 more
openaire   +10 more sources

Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]

open access: yesThe Journal of cell biology, 1983
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C.   +1 more
openaire   +4 more sources

Artificial chromosomes [PDF]

open access: yesExperimental Cell Research, 2020
International ...
Fachinetti, Daniele   +2 more
openaire   +4 more sources

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]

open access: yes, 2015
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco   +9 more
core   +3 more sources

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