Results 21 to 30 of about 1,591,255 (208)

The radial arrangement of the human chromosome 7 in the lymphocyte cell nucleus is associated with chromosomal band gene density [PDF]

, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ Springer-Verlag 2008.In the nuclei of human lymphocytes, chromosome territories are distributed according to the average gene density of ...
A Bolzer, A Ono, AM Boutanaev, B Dutrillaux, BA Boggs, C Federico, C Federico, C Federico, C Federico, C Federico, Catia Daniela Cantarella, CM Clemson, Concetta Federico, D Zink, E Lukasova, ED Andrulis, EV Volpi, G Bernardi, G D’Onofrio, H Tanabe, H Tanabe, HA Foster, I Solovei, IHGSC (International Human Genome Sequencing Consortium), J Ferreira, J Strouboulis, J Zhou, JA Croft, JJ Roix, JM Bridger, K Kupper, KE Brown, L Andreozzi, M Cockell, M Costantini, M Neusser, N Gilbert, N Sadoni, NV Petrova, Patrizia Di Mare, PS Masny, S Boyle, S D’Antoni, S Saccone, S Saccone, S Saccone, S Saccone, Sabrina Tosi, Salvatore Saccone, SW Scherer, T Cremer, TS Furey, U Francke, WA Bickmore   +53 more
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Chromosome Structure: Coiling up chromosomes [PDF]

Current Biology, 1995
The mechanism by which eukaryotic chromosomes condense as cells enter mitosis has long been inaccessible to molecular biologists. An important clue has now been provided by a ubiquitous protein family, the SMCs.
openaire   +2 more sources

Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model

Scientific Reports, 2023
Dystrophin maintains membrane integrity as a sarcolemmal protein. Dystrophin mutations lead to Duchenne muscular dystrophy, an X-linked recessive disorder.
Yosuke Hiramuki, Satoshi Abe, Narumi Uno, Kanako Kazuki, Shuta Takata, Hitomaru Miyamoto, Haruka Takayama, Kayoko Morimoto, Shoko Takehara, Mitsuhiko Osaki, Jun Tanihata, Shin’ichi Takeda, Kazuma Tomizuka, Mitsuo Oshimura, Yasuhiro Kazuki   +14 more
doaj   +1 more source

The Origin of a New Sex Chromosome by Introgression between Two Stickleback Fishes. [PDF]

, 2019
Introgression is increasingly recognized as a source of genetic diversity that fuels adaptation. Its role in the evolution of sex chromosomes, however, is not well known. Here, we confirm the hypothesis that the Y chromosome in the ninespine stickleback,
Abbott, Alexander, Anders, Bachtrog, Bachtrog, Bachtrog, Bronson, Browning, Carling, Carneiro, Charlesworth, Charlesworth, Choi, Cook, Corcoran, Coyne, Coyne, Danecek, DePristo, Edwards, Glazer, Green, Groves Dixon, Hagen, Irwin, Ishikawa, JanouŠek, Jay, Jombart, Jombart, Jun Kitano, Krueger, Langmead, Li, Li, Lindholm, Love, Luo, Mark Kirkpatrick, Martin, Martin, Martin, Meguro, Melissa Wilson Sayres, Muirhead, Natri, Neafsey, Nei, O’Neill, Payseur, Petit, Presgraves, Quinlan, Ravinet, Ross, Saetre, Sankararaman, Schwander, Sciuchetti, Smit, Stamatakis, Storchová, Stölting, Sun, Takahashi, Takahashi, Toews, Tosi, Toups, Tuttle, van Doorn, Vicoso, von Hippel, Wang, White, Yang, Yoshida, Yoshida, Úbeda   +78 more
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Chromosome breakpoint distribution of damage induced in peripheral blood lymphocytes by densely ionising radiation [PDF]

, 2006
Purpose: To assess the chromosomal breakpoint distribution in human peripheral blood lymphocytes (PBL) after exposure to a low dose of high linear energy transfer (LET) α-particles using the technique of multiplex fluorescence in situ hybridisation (m ...
Anderson, RM, Goodhead, DT, Papworth, DG, Sumption, ND   +3 more
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Mitotic chromosomes

Seminars in Cell & Developmental Biology, 2021
Our understanding of the structure and function of mitotic chromosomes has come a long way since these iconic objects were first recognized more than 140 years ago, though many details remain to be elucidated. In this chapter, we start with the early history of chromosome studies and then describe the path that led to our current understanding of the ...
James R. Paulson, Damien F. Hudson, Fernanda Cisneros-Soberanis, William C. Earnshaw   +3 more
openaire   +2 more sources

The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena

iScience, 2020
Summary: During sexual reproduction in the ciliate, Tetrahymena thermophila, cells of complementary mating type pair (“conjugate”) undergo simultaneous meiosis and fertilize each other.
Takahiko Akematsu, Rosalía Sánchez-Fernández, Felix Kosta, Elisabeth Holzer, Josef Loidl   +4 more
doaj   +1 more source

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11 [PDF]

, 2005
Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional ...
De Preter, K, Vandesompele, J, Menten, B, Carr, P, Fiegler, H, Edsjö, Anders,, Carter, NP, Yigit, N, Waelput, W, Van Roy, N, Bader, S, Påhlman, Sven,, Speleman, F, Lund University.   +13 more
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Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]

, 1984
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
A Chapelle de la, AJ Solari, AJ Solari, BD Young, BR Migeon, C Cremer, CR M�ller, CR M�ller, D Page, DT Denhardt, EMJ Southern, GM Wahl, J Fantes, JBS Haldane, JW Gray, KE Davies, L Zech, LM Kunkel, LM Kunkel, MJ Moses, P Goodfellow, P Leder, P Polani, PK Horan, PL Pearson, PN Dean, PN Dean, PN Goodfellow, PS Burgoyne, PS Gerhard, R Krumlauf, RG Langlois, SP Daiger, T Mohandas, U M�ller   +34 more
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Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]

, 1986
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner, AHN Hopman, AL Jørgensen, AR Mitchell, B Trask, BU Zabel, CD Bloomfield, D Pinkel, GA Rappold, GA Rappold, H Hoehn, H. D. Hager, H. P. Scholl, HF Willard, J Wolfe, J. Landegent, JC Wu, JE Landegent, JE Landegent, L Manuelidis, LA Herzenberg, M Schardin, M Schmid, M Spaeter, M. Schardin, M. van der Ploeg, MM LeBeau, P Devilee, P Devilee, P. Devilee, P. Pearson, T Cremer, T. Cremer, W Schempp   +33 more
core   +1 more source