Results 11 to 20 of about 895,255 (269)

Targeting chromosome trisomy for chromosome editing [PDF]

open access: yesScientific Reports, 2021
AbstractA trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in chicken DT40 cells.
Takuya Abe   +3 more
openaire   +3 more sources

Chromosome Painting of Mouse Chromosomes [PDF]

open access: yes, 2018
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
openaire   +4 more sources

Chromosomes, chromosome anomalies [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Educational Items on Chromosomes, chromosome anomalies.
Huret, JL, Leonard, C, Savage, JRK
openaire   +2 more sources

THE CHROMOSOMES OF THE CERCOPIDÆ [PDF]

open access: yesThe Biological Bulletin, 1913
1. The chromosomes of Philœnus spumarius and Aphrophora spumaria were studied and compared with those of the four other species of Cercopidae previously worked out. All have an odd chromosome which does not divide in the first spermatocyte division.
openaire   +2 more sources

Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting [PDF]

open access: yesGenetics Selection Evolution, 2003
A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection. For the porcine inversion, probes specific for p arms and q arms were produced and hybridised simultaneously on metaphases of a heterozygote ...
Pinton, Alain   +2 more
openaire   +7 more sources

Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model

open access: yesScientific Reports, 2023
Dystrophin maintains membrane integrity as a sarcolemmal protein. Dystrophin mutations lead to Duchenne muscular dystrophy, an X-linked recessive disorder.
Yosuke Hiramuki   +14 more
doaj   +1 more source

The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena

open access: yesiScience, 2020
Summary: During sexual reproduction in the ciliate, Tetrahymena thermophila, cells of complementary mating type pair (“conjugate”) undergo simultaneous meiosis and fertilize each other.
Takahiko Akematsu   +4 more
doaj   +1 more source

Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]

open access: yesThe Journal of cell biology, 1983
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C.   +1 more
openaire   +3 more sources

Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation

open access: yeseLife, 2021
The Rad53 DNA checkpoint protein kinase plays multiple roles in the budding yeast cell response to DNA replication stress. Key amongst these is its enigmatic role in safeguarding DNA replication forks.
Allison W McClure, John FX Diffley
doaj   +1 more source

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