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Targeting chromosome trisomy for chromosome editing [PDF]
AbstractA trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in chicken DT40 cells.
Takuya Abe +3 more
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Chromosome Painting of Mouse Chromosomes [PDF]
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
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Chromosomes, chromosome anomalies [PDF]
Educational Items on Chromosomes, chromosome anomalies.
Huret, JL, Leonard, C, Savage, JRK
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THE CHROMOSOMES OF THE CERCOPIDÆ [PDF]
1. The chromosomes of Philœnus spumarius and Aphrophora spumaria were studied and compared with those of the four other species of Cercopidae previously worked out. All have an odd chromosome which does not divide in the first spermatocyte division.
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Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting [PDF]
A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection. For the porcine inversion, probes specific for p arms and q arms were produced and hybridised simultaneously on metaphases of a heterozygote ...
Pinton, Alain +2 more
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Dystrophin maintains membrane integrity as a sarcolemmal protein. Dystrophin mutations lead to Duchenne muscular dystrophy, an X-linked recessive disorder.
Yosuke Hiramuki +14 more
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The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena
Summary: During sexual reproduction in the ciliate, Tetrahymena thermophila, cells of complementary mating type pair (“conjugate”) undergo simultaneous meiosis and fertilize each other.
Takahiko Akematsu +4 more
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Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C. +1 more
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Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
The Rad53 DNA checkpoint protein kinase plays multiple roles in the budding yeast cell response to DNA replication stress. Key amongst these is its enigmatic role in safeguarding DNA replication forks.
Allison W McClure, John FX Diffley
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