Results 221 to 230 of about 1,078,812 (267)

Chromosome imprinting and the mammalian X chromosome

Nature, 1975
Chromosome imprinting is the process by which one of two genetically homologous chromosomes is predetermined to function differently from the other at a subsequent stage in development. In the coccid insects, imprinting occurs in the egg, at the time of fertilisation; it probably occurs at the same time and site in mammals, and possibly also in Sciara.
H S, Chandra, S W, Brown
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Chromosomal Instability

Current Opinion in Oncology, 2004
This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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The human Y chromosome: a masculine chromosome

Current Opinion in Genetics & Development, 2006
Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production.
Michiel J, Noordam, Sjoerd, Repping
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Chromosome 18 replaced by two ring chromosomes of chromosome 18 origin

Human Genetics, 2003
We here describe the first example of the replacement of an autosome by two ring chromosomes originating from the missing chromosome, presented in a patient with a single chromosome 18 and two additional ring chromosomes. Detailed fluorescence in situ hybridization (FISH) analysis revealed the chromosome 18 origin of both ring chromosomes and ...
K, Miller, B, Pabst, H, Ritter, P, Nürnberg, R, Siebert, J, Schmidtke, M, Arslan-Kirchner   +6 more
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Chromosom I, Chromosom II, Chromosom III, Chromosom IV; [ca. 1950]

2023
Auf Papier mit ...
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Chromosome Conformation Capture of Mitotic Chromosomes

2023
Despite more than a century of intensive study of mitotic chromosomes, their three-dimensional organization remains enigmatic. The last decade established Hi-C as a method of choice for study of spatial genome-wide interactions. Although its utilization has been focused mainly on studying genomic interactions in interphase nuclei, the method can be ...
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Sex Chromosomes and Sex Chromosome Abnormalities

Clinics in Laboratory Medicine, 2011
This article focuses on constitutional sex chromosome abnormalities detected by conventional cytogenetics and fluorescence in situ hybridization. The author discusses the two general classifications of abnormalities: numerical and structural. Also included are descriptions of unique aspects of X and Y chromosomes, technological advances in detection ...
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[Chromosomes and chromosome disorders].

Nordisk medicin, 1990
The risk of bearing a child with chromosomal defects increases once the mother reaches the age of 35; the principal indication for chromosomal examination of the fetus is that the pregnant woman is "older". Chromosomal examination of new-born babies is indicated if it is suspected that dysmorphic features may depend on cytogenetic deviation.
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Ring-Chromosomes, Telocentric Chromosomes, Isochromosomes, and B Chromosomes

1980
This chapter is a continuation of the discussion of unusual chromosome types. As mentioned before, the term “unusual” in this connection is a relative term. We very often have a certain concept of things, and whatever deviates from this concept we call “unusual”. Because ring-chromosomes, telocentric chromosomes, isochromosomes, or B chromosomes differ
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THE CHROMOSOMES OF MAN

Human Heredity, 1956
C E, FORD, J L, HAMERTON
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