Results 241 to 250 of about 1,659,623 (343)
The sex chromosome in the house mouse [PDF]
Ronald Aylmer Fisher+2 more
openalex +1 more source
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun+15 more
wiley +1 more source
Optimizing chromosome dispersion quality: the key role of cell density. [PDF]
Gao CX+6 more
europepmc +1 more source
Localisation of chromosome breakage at meiosis [PDF]
H. Rees, J B Thompson
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This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song+37 more
wiley +1 more source
The mitotic chromosome periphery modulates chromosome mechanics. [PDF]
Mendonca T+7 more
europepmc +1 more source
DISPROPORTIONATE SYNTHESIS OF DNA IN A POLYTENE CHROMOSOME REGION
George T. Rudkin, Sally L. Corlette
openalex +1 more source
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang+9 more
wiley +1 more source