Results 251 to 260 of about 1,806,540 (343)

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Genome report: chromosome-scale genome assembly of the olive fly Bactrocera oleae (Diptera: Tephritidae). [PDF]

open access: yesG3 (Bethesda)
Hansen TE   +6 more
europepmc   +1 more source

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

open access: yesAdvanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang   +9 more
wiley   +1 more source

Genetic architecture of cowpea domestication: QTL mapping and comparison shed new light on the dual domestication events. [PDF]

open access: yesG3 (Bethesda)
Dramé D   +10 more
europepmc   +1 more source

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

open access: yesAdvanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani   +20 more
wiley   +1 more source

Chromosome-Level Genomics and Historical Museum Collections Reveal New Insights Into the Population Structure and Chromosome Evolution of Waterbuck. [PDF]

open access: yesMol Ecol
Kirkland C   +12 more
europepmc   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

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