Results 41 to 50 of about 1,768,096 (341)

B Chromosomes – A Matter of Chromosome Drive [PDF]

open access: yesFrontiers in Plant Science, 2017
B chromosomes are supernumerary chromosomes which are often preferentially inherited, deviating from usual Mendelian segregation. The balance between the so-called chromosome drive and the negative effects that the presence of Bs applies on the fitness of their host determines the frequency of Bs in a particular population.
openaire   +3 more sources

The origin of human chromosome 2 analyzed by comparative chromosome mapping with a DNA microlibrary [PDF]

open access: yes, 1994
Fluorescencein situ hybridization (FISH) of microlibraries established from distinct chromosome subregions can test the evolutionary conservation of chromosome bands as well as chromosomal rearrangements that occurred during primate evolution and will ...
A Baldini   +32 more
core   +1 more source

Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase

open access: yesNature Communications, 2019
RAD51 assembly on single-stranded DNAs is an important step in the homology-dependent repair of DNA damage. Here authors reveal a role for the human RAD51 paralogue, SWSAP1, as a regulator of RAD51 assembly, by antagonizing RAD51 remodeller, FIGNL1 AAA + 
Kenichiro Matsuzaki   +3 more
doaj   +1 more source

On the origin of trisomy 21 Down syndrome [PDF]

open access: yes, 2008
Background: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability.
Hultén, Maj A.   +6 more
core   +2 more sources

A global view of substrate phosphorylation and dephosphorylation during budding yeast mitotic exit

open access: yesMicrobial Cell, 2018
The cell cycle is the process by which a cell duplicates its DNA during S-phase and divides its chromosomes during M-phase, creating two genetically identical daughter cells.
Sandra A. Touati, Frank Uhlmann
doaj   +1 more source

Detection of quantitative trait loci for locomotion and osteochondrosis-related traits in Large White x Meishan pigs. [PDF]

open access: yes, 2003
Data from the F2 generation of a Large White (LW) 5 Meishan (MS) crossbred population were analysed to detect quantitative trait loci (QTL) for leg and gait scores, osteochondrosis and physis scores.
Archibald, Alan   +6 more
core  

Chromosome breakage after G2 checkpoint release [PDF]

open access: yes, 2006
DNA double-strand break (DSB) repair and checkpoint control represent distinct mechanisms to reduce chromosomal instability. Ataxia telangiectasia (A-T) cells have checkpoint arrest and DSB repair defects. We examine the efficiency and interplay of ATM's
Beucher, Andrea   +8 more
core   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The 160 bp insertion in the promoter of Rht-B1i plays a vital role in increasing wheat height

open access: yesFrontiers in Plant Science, 2016
The extensive use of two alleles (Rht-B1b and Rht-D1b) at the Rht-1 locus in wheat allowed dramatic increases in yields, triggering the so-called Green Revolution. Here, we found that a new natural allelic variation (Rht-B1i) containing a single missense
Xueyuan eLou   +8 more
doaj   +1 more source

An evaluation of genotyping by sequencing (GBS) to map the Breviaristatum-e (ari-e) locus in cultivated barley [PDF]

open access: yes, 2014
: We explored the use of genotyping by sequencing (GBS) on a recombinant inbred line population (GPMx) derived from a cross between the two-rowed barley cultivar ‘Golden Promise’ (ari-e.GP/Vrs1) and the six-rowed cultivar ‘Morex’ (Ari-e/vrs1) to map ...
Bayer, Micha   +8 more
core   +4 more sources

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