Results 41 to 50 of about 1,598,920 (365)

Dynamic chromatin regulatory programs during embryogenesis of hexaploid wheat

open access: yesGenome Biology, 2023
Background Plant and animal embryogenesis have conserved and distinct features. Cell fate transitions occur during embryogenesis in both plants and animals. The epigenomic processes regulating plant embryogenesis remain largely elusive.
Long Zhao   +13 more
doaj   +1 more source

Centromere function in asymmetric cell division in Drosophila female and male germline stem cells

open access: yesOpen Biology, 2021
The centromere is the constricted chromosomal region required for the correct separation of the genetic material at cell division. The kinetochore protein complex assembles at the centromere and captures microtubules emanating from the centrosome to ...
Antje M. Kochendoerfer   +2 more
doaj   +1 more source

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]

open access: yes, 1986
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner   +33 more
core   +1 more source

Role of the Number of Microtubules in Chromosome Segregation during Cell Division [PDF]

open access: yesPLoS ONE 10(10): e0141305 (2015), 2015
Faithful segregation of genetic material during cell division requires alignment of chromosomes between two spindle poles and attachment of their kinetochores to each of the poles. Failure of these complex dynamical processes leads to chromosomal instability (CIN), a characteristic feature of several diseases including cancer.
arxiv   +1 more source

ATR Activates the S-M Checkpoint during Unperturbed Growth to Ensure Sufficient Replication Prior to Mitotic Onset

open access: yesCell Reports, 2013
Cells must accurately replicate and segregate their DNA once per cell cycle in order to successfully transmit genetic information. During S phase in the presence of agents that cause replication stress, ATR-dependent checkpoints regulate origin firing ...
John Kenneth Eykelenboom   +6 more
doaj   +1 more source

Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery

open access: yesScientific Reports, 2022
Homology-directed repair-mediated knock-in (HDR-KI) in combination with CRISPR-Cas9-mediated double strand break (DSB) leads to high frequency of site-specific HDR-KI. While this characteristic is advantageous for generating genetically modified cellular
Kyotaro Yamazaki   +10 more
doaj   +1 more source

The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts. [PDF]

open access: yes, 2003
Chromosome condensation is required for the physical resolution and segregation of sister chromatids during cell division, but the precise role of higher order chromatin structure in mitotic chromosome functions is unclear.
Deehan, Renee   +3 more
core   +4 more sources

B Chromosomes – A Matter of Chromosome Drive [PDF]

open access: yesFrontiers in Plant Science, 2017
B chromosomes are supernumerary chromosomes which are often preferentially inherited, deviating from usual Mendelian segregation. The balance between the so-called chromosome drive and the negative effects that the presence of Bs applies on the fitness of their host determines the frequency of Bs in a particular population.
openaire   +3 more sources

A global view of substrate phosphorylation and dephosphorylation during budding yeast mitotic exit

open access: yesMicrobial Cell, 2018
The cell cycle is the process by which a cell duplicates its DNA during S-phase and divides its chromosomes during M-phase, creating two genetically identical daughter cells.
Sandra A. Touati, Frank Uhlmann
doaj   +1 more source

Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics

open access: yesNature Communications, 2020
Despite tremendous genomic resources in the Arabidopsis community, only a few whole genome de novo assemblies are available. Here, the authors report chromosome-level reference-quality assemblies of seven A.
Wen-Biao Jiao, Korbinian Schneeberger
doaj   +1 more source

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