Dynamic chromatin regulatory programs during embryogenesis of hexaploid wheat
Background Plant and animal embryogenesis have conserved and distinct features. Cell fate transitions occur during embryogenesis in both plants and animals. The epigenomic processes regulating plant embryogenesis remain largely elusive.
Long Zhao+13 more
doaj +1 more source
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells
The centromere is the constricted chromosomal region required for the correct separation of the genetic material at cell division. The kinetochore protein complex assembles at the centromere and captures microtubules emanating from the centrosome to ...
Antje M. Kochendoerfer+2 more
doaj +1 more source
Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner+33 more
core +1 more source
Role of the Number of Microtubules in Chromosome Segregation during Cell Division [PDF]
Faithful segregation of genetic material during cell division requires alignment of chromosomes between two spindle poles and attachment of their kinetochores to each of the poles. Failure of these complex dynamical processes leads to chromosomal instability (CIN), a characteristic feature of several diseases including cancer.
arxiv +1 more source
Cells must accurately replicate and segregate their DNA once per cell cycle in order to successfully transmit genetic information. During S phase in the presence of agents that cause replication stress, ATR-dependent checkpoints regulate origin firing ...
John Kenneth Eykelenboom+6 more
doaj +1 more source
Homology-directed repair-mediated knock-in (HDR-KI) in combination with CRISPR-Cas9-mediated double strand break (DSB) leads to high frequency of site-specific HDR-KI. While this characteristic is advantageous for generating genetically modified cellular
Kyotaro Yamazaki+10 more
doaj +1 more source
The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts. [PDF]
Chromosome condensation is required for the physical resolution and segregation of sister chromatids during cell division, but the precise role of higher order chromatin structure in mitotic chromosome functions is unclear.
Deehan, Renee+3 more
core +4 more sources
B Chromosomes – A Matter of Chromosome Drive [PDF]
B chromosomes are supernumerary chromosomes which are often preferentially inherited, deviating from usual Mendelian segregation. The balance between the so-called chromosome drive and the negative effects that the presence of Bs applies on the fitness of their host determines the frequency of Bs in a particular population.
openaire +3 more sources
A global view of substrate phosphorylation and dephosphorylation during budding yeast mitotic exit
The cell cycle is the process by which a cell duplicates its DNA during S-phase and divides its chromosomes during M-phase, creating two genetically identical daughter cells.
Sandra A. Touati, Frank Uhlmann
doaj +1 more source
Despite tremendous genomic resources in the Arabidopsis community, only a few whole genome de novo assemblies are available. Here, the authors report chromosome-level reference-quality assemblies of seven A.
Wen-Biao Jiao, Korbinian Schneeberger
doaj +1 more source