Results 81 to 90 of about 1,311,035 (215)

XX/XY Sex Chromosomes in the South American Dwarf Gecko (\u3cem\u3eGonatodes humeralis\u3c/em\u3e) [PDF]

open access: yes, 2018
Sex-specific genetic markers identified using restriction site-associated DNA sequencing, or RADseq, permits the recognition of a species’ sex chromosome system in cases where standard cytogenetic methods fail.
Gamble, Tony   +6 more
core   +1 more source

The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena

open access: yesiScience, 2020
Summary: During sexual reproduction in the ciliate, Tetrahymena thermophila, cells of complementary mating type pair (“conjugate”) undergo simultaneous meiosis and fertilize each other.
Takahiko Akematsu   +4 more
doaj  

53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process

open access: yesNature Communications, 2018
Chromosome instability is associated with cancer formation. Here the authors identify in cultured human cancer cells a non-canonical DNA bridge breakage pathway leading to chromosome missegregation and rearrangements triggered by sister DNA ...
Ankana Tiwari   +2 more
doaj   +1 more source

Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes

open access: yesPharmacology Research & Perspectives, 2022
UDP‐glucuronosyltransferases (UGTs) catalyze the conjugation of various substrates with sugars. Since the UGT2 family forms a large cluster spanning 1.5 Mb, transgenic mouse lines carrying the entire human UGT2 family have not been constructed because of
Kaoru Kobayashi   +9 more
doaj   +1 more source

Resolving the degree of order in the bacterial chromosome using a statistical physics approach [PDF]

open access: yesarXiv, 2020
While bacterial chromosomes were long thought to be amorphous, recent experiments reveal pronounced organizational features. However, the extent of bacterial chromosome organization remains unclear. Here, we develop a fully data-driven maximum entropy approach to extract the distribution of single-cell chromosome conformations from experimental ...
arxiv  

Why Y chromosome is shorter and women live longer? [PDF]

open access: yesEur. Phys. J. B 65, 149-153 (2008), 2008
We have used the Penna ageing model to analyze how the differences in evolution of sex chromosomes depend on the strategy of reproduction. In panmictic populations, when females (XX) can freely choose the male partner (XY) for reproduction from the whole population, the Y chromosome accumulates defects and eventually the only information it brings is a
arxiv   +1 more source

Double in situ hybridization in combination with digital image analysis: A new approach to study interphase chromosome topography [PDF]

open access: yes, 1989
Double in situ hybridization with mercurated and biotinylated chromosome specific DNA probes in combination with digital image analysis provides a new approach to compare the distribution of homologous and nonhomologous chromosome targets within ...
Cremer, Christoph   +9 more
core   +1 more source

Improving the Search by Encoding Multiple Solutions in a Chromosome [PDF]

open access: yesEvolutionary Machine Design, Nova Science Publisher, New-York, edited by Nadia Nedjah (et al.), pp. 81-107, 2004, 2021
We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the chromosome decoding process must have the same complexity as in the case of a single solution in a chromosome ...
arxiv  

Chromosome breakage after G2 checkpoint release [PDF]

open access: yes, 2006
DNA double-strand break (DSB) repair and checkpoint control represent distinct mechanisms to reduce chromosomal instability. Ataxia telangiectasia (A-T) cells have checkpoint arrest and DSB repair defects. We examine the efficiency and interplay of ATM's
Beucher, Andrea   +8 more
core   +4 more sources

Chromosome Evolution: The Junction of Mammalian Chromosomes in the Formation of Mouse Chromosome 10 [PDF]

open access: yesGenome Research, 2000
During evolution, chromosomes are rearranged and become fixed into new patterns in new species. The relatively conservative nature of this process supports predictions of the arrangement of ancestral mammalian chromosomes, but the basis for these rearrangements is unknown.
Eda Malaj   +6 more
openaire   +3 more sources

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