Results 231 to 240 of about 1,193,636 (302)

Single‐Cell Transcriptomic Atlases of Camels and Cattle Unravel Molecular Evolution of Digestive and Metabolic Systems

Advanced Science, EarlyView.
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi, Huiquan Shan, Haoping Wang, Xi Guo, Houcheng Li, Bo Han, Senlin Zhu, Fei Wang, Guanghui Tan, Zhannur Niyazbekova, Jilong Ren, Yaqi Zhou, Qi Zhang, Weijie Zheng, Minghui Jia, Ao Zhang, Xuesha Cao, Huizeng Sun, Dongxiao Sun, Lingzhao Fang, Yi Zheng, Xihong Wang, Yu Jiang   +22 more
wiley   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

A case report on atypical chromosomal variations in Turner syndrome. [PDF]

Mol Cytogenet
Aliazami F, Farhud DD, Zarif-Yeganeh M, Shahmoradi SS, Tajik B, Jaryani S.   +5 more
europepmc   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Phenotypic and genetic resistance to Septoria blotch disease in European wheat varieties. [PDF]

Plant Genome
Copeland C, Isidro Y Sánchez J, Fanelli H, Doohan FM.   +3 more
europepmc   +1 more source

Active maintenance of meiosis-specific chromosome structures in <i>Caenorhabditis elegans</i> by the deubiquitinase DUO-1. [PDF]

Proc Natl Acad Sci U S A
Strand LG, Choi CP, McCoy S, Nsamba ET, Silva N, Villeneuve AM.   +5 more
europepmc   +1 more source

A haplotype-resolved, chromosome-scale genome assembly for the southern live oak, Quercus virginiana. [PDF]

G3 (Bethesda)
Aközbek L, Meharg Z, Abendroth-McGhee J, Akinsipe T, Dhakal R, Gladstone N, Pervaiz Z, Patel S, Rossi G, Rutland CA, Bendickson C, Kranz A, Martinson EO, Egan SP, Feltus FA, Clarke DJ, Lovell JT, Webber J, Boston LB, Hale H, McCoy H, Grimwood J, Carey SB, Goertzen L, Harkess A.   +24 more
europepmc   +1 more source

Across-breed analyses of genome-wide association studies for stature and mammary gland morphology in cattle reveal pleiotropic effects of the Friesian POLLED haplotype. [PDF]

Genet Sel Evol
Watson N, He Q, Kadri NK, Leonard AS, Seefried FR, Pausch H.   +5 more
europepmc   +1 more source