Results 61 to 70 of about 812,203 (315)
Cytogenetic Findings in Mentally Retarded Iranian Patients
Balkan Journal of Medical Genetics, 2012 We conducted a cytogenetic study on 865 individuals with idiopathic mental retardation (MR) who were admitted to the Cytogenetics Department of the Iran Blood Transfusion Organisation (IBTO) Research Centre, Tehran, Iran; these were performed on blood ...
Nasiri F. +5 more
doaj +1 more source
ChrSNet: Chromosome Straightening using Self-attention Guided Networks [PDF]
arXiv, 2022 Karyotyping is an important procedure to assess the possible existence of chromosomal abnormalities. However, because of the non-rigid nature, chromosomes are usually heavily curved in microscopic images and such deformed shapes hinder the chromosome analysis for cytogeneticists.
arxiv
Nonrandom de novo chromosome aberrations in human lymphocytes and amniotic cells.
Hereditas, 2008 The incidences and types of chromosome aberrations in single cells of individuals with a normal chromosome constitution were studied in two cell types, viz. lymphocytes and amniotic cells.
H. Petersson, F. Mitelman
semanticscholar +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Galician Medical Journal, 2017 The frequency and spectrum of chromosomal aberrations, acrocentric chromosome associations among 264 long livers with arterial hypertension and osteoarthritis residing in the Carpathian region were analyzed.
Ruslan Kozoviy
doaj +1 more source
Combining chromosomal arm status and significantly aberrant genomic locations reveals new cancer subtypes [PDF]
arXiv, 2008 Many types of tumors exhibit chromosomal losses or gains, as well as local amplifications and deletions. Within any given tumor type, sample specific amplifications and deletionsare also observed. Typically, a region that is aberrant in more tumors,or whose copy number change is stronger, would be considered as a more promising candidate to be ...
arxiv
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
RUDN Journal of Ecology and Life Safety, 2009 The aim of the research is the study of the regularity of the phenotypic manifestation of the level of chromosome aberrations and of the transcriptional activity of chromosomes' kernel-forming areas on the example of arterial hypertension development ...
I N Medvedev, I V Amelina
doaj
Haematologica, 2018 Chronic lymphocytic leukemia is associated with a highly heterogeneous disease course in terms of clinical outcomes and responses to chemoimmunotherapy.
E. Campo +7 more
semanticscholar +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source