This work is about the setup of an in vitro system to report low-dose of X-rays as measured as cytogenetic damage. Q- and m-FISH, for telomere length and chromosome instability analysis respectively, were compared to evaluate their sensitivity in the low-
Dino eNieri +4 more
doaj +1 more source
m-FISH analysis reveals complexity of chromosome aberrations in individuals occupationally exposed with internal plutonium: A pilot study to assess the relevance of complex aberrations as biomarkers of exposure to high-LET α particles [PDF]
We recently demonstrated that a significant proportion of apparently stable insertions induced after exposure to a mean of 1 α particle/cell, detected using 3-colour FISH, were part of larger unstable complexes when visualised by 24-colour FISH ...
Anderson, RM +5 more
core
We evaluated the genetic changes in bladder cancer biopsy by fluorescence in situ hybridization (FISH) and related them to stage and grade of the tumor, ploidy (FCM) and clinical outcome, to determine a simple method to identify tumors with a poorer ...
AM Cianciulli +8 more
doaj +1 more source
Objective: Objective: Chronic myeloid leukemia (CML) is a clonal hematologic disorder characterized by t(9;22) translocation, in which cytogenetic aberrations can occur in Ph(+) and (-) clones. These aberrations develop due to clonal evolution as well as
Sevgi Işık +10 more
doaj +1 more source
Global methylation status of sperm DNA in carriers of chromosome structural aberrations
Male infertility might be clearly associated with aberrant DNA methylation patterns in human spermatozoa. An association between oxidative stress and the global methylation status of the sperm genome has also been suggested.
Marta Olszewska +7 more
doaj +1 more source
Aneuploidy among androgenic progeny of hexaploid triticale (XTriticosecale Wittmack). [PDF]
Doubled haploids are an established tool in plant breeding and research. Of several methods for their production, androgenesis is technically simple and can efficiently produce substantial numbers of lines.
Lukaszewski, Adam J +3 more
core +3 more sources
Chromosome aberrations and sister chromatid exchanges in lead‐exposed workers
Chromosomal aberrations and sister chromatid exchanges (SCEs) were studied in peripheral blood lymphocytes of 18 workers exposed to lead in a smeltery and 12 unexposed controls.
J. Mäki‐Paakkanen +2 more
semanticscholar +1 more source
Cytogenetic Findings in Mentally Retarded Iranian Patients
We conducted a cytogenetic study on 865 individuals with idiopathic mental retardation (MR) who were admitted to the Cytogenetics Department of the Iran Blood Transfusion Organisation (IBTO) Research Centre, Tehran, Iran; these were performed on blood ...
Nasiri F. +5 more
doaj +1 more source
Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells? [PDF]
Field cancerization effects as well as isolated tumor cell foci extending well beyond the invasive tumor margin have been described previously to account for local recurrence rates following breast conserving surgery despite adequate surgical margins and
Benz, Christopher C +8 more
core +2 more sources
Herbal Remedies for Combating Irradiation: a Green Antiirradiation Approach [PDF]
Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane.
Choong, Y. S. +8 more
core +1 more source

