Results 111 to 120 of about 2,532,538 (409)
Further delineation of complex chromosomal rearrangements in fertile male using multicolor banding
Molecular Cytogenetics, 2008 Background Complex chromosomal rearrangements (CCRs) are defined as structural chromosomal rearrangements with at least three breakpoints and exchange of genetic material between two or more chromosomes. Complex chromosomal translocations are rarely seen
Weise Anja +2 more
doaj +1 more source
Resolving the degree of order in the bacterial chromosome using a statistical physics approach [PDF]
arXiv, 2020 While bacterial chromosomes were long thought to be amorphous, recent experiments reveal pronounced organizational features. However, the extent of bacterial chromosome organization remains unclear. Here, we develop a fully data-driven maximum entropy approach to extract the distribution of single-cell chromosome conformations from experimental ...
arxiv
BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancer [PDF]
, 2009 Structural chromosome aberrations are known hallmarks of many solid tumors. In the papillary form of thyroid cancer (PTC), for example, activation of the receptor tyrosine kinase (RTK) genes, RET and neurotrophic tyrosine kinase receptor type I (NTRK1)
Baumgartner, Adolf +6 more
core +2 more sources
SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway
Advanced Science, EarlyView.Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang +9 more
wiley +1 more source
ZooKeys, 2013 In spite of various cytogenetic works on suborder Heteroptera, the chromosome organization, function and its evolution in this group is far from being fully understood.
Vikas Suman, Harbhajan Kaur
doaj +1 more source
Aneuploidy among androgenic progeny of hexaploid triticale (XTriticosecale Wittmack). [PDF]
, 2010 Doubled haploids are an established tool in plant breeding and research. Of several methods for their production, androgenesis is technically simple and can efficiently produce substantial numbers of lines.
Lukaszewski, Adam J +3 more
core +3 more sources
A comparative chromosome‐banding study in the silver fox, the blue fox, and their hybrids
, 1982 The silver fox (Vulpes fulvus Desm.) (2n = 34 to 42) and the blue fox (Alopex lagopus L.) (2n = 48 to 50) represent different genera but, nevertheless, produce viable, though sterile, offspring.
A. Mäkinen, I. Gustavsson
semanticscholar +1 more source
Advanced Science, EarlyView.High QSOX2 enhances stemness, drug resistance, and metastasis of ESCC cells. QSOX2‐mediated disulfide bond modification activates mTOR/c‐Myc signaling. CAFs‐secreted IGF‐1 drives mTOR/c‐Myc/QSOX2 positive feedback loop. Combining Ebselen, rapamycin, and cisplatin induces tumor dormancy in mice.
Wo‐Ming Chen +12 more
wiley +1 more source
Case Reports in Genetics, 2017 Interstitial deletions of 4q are rarely reported, vary in size, and have limited genotype-phenotype correlations. Here, genome-wide array CGH analysis identified a 21.6 Mb region of copy number loss at 4q12-q21.1 in a patient diagnosed with dysmorphism ...
J. Carter +4 more
doaj +1 more source
Chromosomal Structural Abnormality Diagnosis by Homologous Similarity [PDF]
Pathogenic chromosome abnormalities are very common among the general population. While numerical chromosome abnormalities can be quickly and precisely detected, structural chromosome abnormalities are far more complex and typically require considerable efforts by human experts for identification.
arxiv +1 more source