Results 301 to 310 of about 462,672 (344)
Some of the next articles are maybe not open access.
Chromosomal deletions in the myelodysplastic syndrome
Leukemia Research, 1992Karyotypic abnormalities in primary myelodysplastic syndrome (P-MDS) are less frequent than in secondary myelodysplasia. A review of the literature involving over 3000 reported cases, shows the incidence of karyotypically abnormal clones at presentation in nearly 48% of cases.
openaire +2 more sources
2009
Several, acquired, non-random chromosomal deletions have been characterized in acute myelogenous leukemia (AML). While the deletion limits vary among patients, there are consistent regions of overlap among the deleted segments between patients. Furthermore, chromosomal deletions are achieved frequently by unbalanced translocations between two and more ...
openaire +2 more sources
Several, acquired, non-random chromosomal deletions have been characterized in acute myelogenous leukemia (AML). While the deletion limits vary among patients, there are consistent regions of overlap among the deleted segments between patients. Furthermore, chromosomal deletions are achieved frequently by unbalanced translocations between two and more ...
openaire +2 more sources
Interstitial deletion of chromosome 21
Clinical Genetics, 1982A case report of an infant with the karyotype 46, XX, int del (21) (q21q22) is presented, in whom the 21 deletion syndrome or “antimongolism” is well defined clinically.
N, Modi, K E, Buckton
openaire +2 more sources
Chromosomal Deletions in Streptococcus mutans
1997The oral bacterium Streptococcus mutans possesses the ability to ferment a wide range of carbohydrates, which results in the production of acids that can cause demineralisation of tooth enamel and subsequent dental caries. However, it has been shown that approximately 11% of independent isolates of S.
C R, Lewis, R R, Russell
openaire +2 more sources
Chromosome healing of constitutional chromosome deletions studied by microdissection
Cytogenetic and Genome Research, 1998Broken chromosomes are highly unstable and are subject to chromosome fusion or loss. As an exception, healing of human chromosomes occurs which can lead to constitutional or acquired terminal chromosome deletion disorders. Both <i>de novo</i> telomere addition at the breakpoint and telomere capture have been implicated as healing mechanisms.
J R, Vermeesch +4 more
openaire +2 more sources
Short arm deletion of chromosome 14
Human Genetics, 19723 cases with a Do-chromosome, designated by autoradiography as a No. 14, are presented by the authors. The first case was a mentally retarded boy with minor malformations. Cases 2 and 3 had normal phenotypes and were detected by cytogenetic investigation of family members of a mentally retarded boy with a ring G chromosome.
I, Emerit +4 more
openaire +2 more sources
Interstitial deletion of chromosome 11q in a pineoblastoma
Cancer Genetics and Cytogenetics, 1989A case of pineoblastoma with an interesting cytogenetic abnormality is reported. Chromosomal analysis of cultured cells from the tumor of a 10-week-old white male revealed an interstitial deletion of the long arm of chromosome 11, del(11)(q13.1q13.5). Tumors of the pineal region are relatively rare, and this is the first report of a pineoblastoma with ...
C, Sreekantaiah +3 more
openaire +2 more sources
Deletion of the short arms of chromosome 20
Human Genetics, 1976A 46, XX, del(20) (p11) karyotype (Paris Conference, 1971) was identified in an 11-month-old French-Canadian girl with a dysmorphic syndrome, multiple congenital anomalies, psychomotor and growth retardation. Both parents had normal phenotype and karyotype.
D K, Kalousek, S, Thérien
openaire +2 more sources
Deletion of chromosome 13 in leiomyomas of the uterus
Cancer Genetics and Cytogenetics, 1991We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13. To our knowledge this cytogenetic abnormality as a single change has not been reported previously. One of our cases showed a del(13)(q14q32) and the other a del(13)(q13q33).
A M, Meloni, U, Surti, A A, Sandberg
openaire +2 more sources
Seckel syndrome with chromosomal 18 deletion
The Indian Journal of Pediatrics, 2009Four case records of patients with Seckel Syndrome (SS) were retrieved. Typical of bird headed dwarfism was seen in all. Chromosome 18 deletion was seen in one child with SS. MRI abnormalities were detected in 3 patients. Cytogenetic studies and neuroimaging is likely to provide important diagnostic and prognostic information.
Inusha, Panigrahi +4 more
openaire +2 more sources