Results 181 to 190 of about 4,160,939 (294)

Complete reference genomes of <i>Haemophilus ducreyi</i> isolates ITG3105, CIP76118, and TMA3542, using Oxford Nanopore and Illumina sequencing. [PDF]

Microbiol Resour Announc
Golparian D, Schröder D, Unemo M.
europepmc   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Mapping Fusarium wilt and sterility mosaic disease resistance-associated genomic regions and haplotype variants in pigeonpea. [PDF]

BMC Plant Biol
Rangari SK, Krishnappa S, Sharma M, Sharma VK, Lohithaswa HC, Dube N, Gangurde SS, Sharma V, Abbai R, Bomma N, Belliappa S, Bhutia KL, Thudi M, Gangashetty PI, Pandey MK.   +14 more
europepmc   +1 more source

New molecular evidence on genome relationships and chromosome identification in fescue (Festuca) and ryegrass (Lolium)

Heredity, 1998
I. Pašakinskienė, K. Anamthawat-Jónsson, M. Humphreys, V. Paplauskienė, R. N. Jones   +4 more
semanticscholar   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Stepwise construction of the path to doubled haploid breeding in sorghum. [PDF]

Sci Adv
Sui Y, Sun Y, Cheng Z, Li Y, Li K, Zhang X, Yin T, Yang S, Li G, Liu M, Tang S, Wu C.   +11 more
europepmc   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

A digital microfluidic platform for cell-based non-invasive testing. [PDF]

iScience
Siriwardena D, Dryden MDM, Chamberlain MD, Taylor C, Dupoiron L, Gulati S, Abbas F, Lamanna J, Chitayat D, Wheeler AR, Greenfeld E.   +10 more
europepmc   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

A Deep Dive into Allium Satellite DNAs: Expansion and Characterization of the <i>Allium cepa</i> and <i>Allium fistulosum</i> Satellitomes. [PDF]

Int J Mol Sci
Ermolaev A, Khrustaleva L, Kudryavtseva N.   +2 more
europepmc   +1 more source