Results 111 to 120 of about 2,043,269 (377)

Physical and Genetic Mapping of the SPO2 Prophage on the Chromosome of Bacillus subtilis 168 [PDF]

, 1969
Joseph Inselburg, T. Eremenko‐Volpe, L. Greenwald, W. L. Meadow, Julius Marmur   +4 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Syntenic relationships between cucumber (Cucumis sativus L.) and melon (C. melo L.) chromosomes as revealed by comparative genetic mapping

BMC Genomics, 2011
Background Cucumber, Cucumis sativus L. (2n = 2 × = 14) and melon, C. melo L. (2n = 2 × = 24) are two important vegetable species in the genus Cucumis (family Cucurbitaceae).
Staub Jack E, Zalapa Juan, Garcia-Mas Jordi, Li Yuhong, Yang Luming, Cuevas Hugo E, Li Dawei, Luan Feishi, Reddy Umesh, He Xiaoming, Gong Zhenhui, Weng Yiqun   +11 more
doaj   +1 more source

Genetic Mapping of the Locus Controlling Structural Variations of Murine C3 in the Chromosome 17 [PDF]

, 1979
S Natsuume-Sakai, Jun-ichiro Hayakawa, Shigetoyo Amano, Morinobu Takahashi   +3 more
openalex   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

DeepACEv2: Automated Chromosome Enumeration in Metaphase Cell Images Using Deep Convolutional Neural Networks [PDF]

arXiv, 2019
Chromosome enumeration is an essential but tedious procedure in karyotyping analysis. To automate the enumeration process, we develop a chromosome enumeration framework, DeepACEv2, based on the region based object detection scheme. The framework is developed following three steps. Firstly, we take the classical ResNet-101 as the backbone and attach the
arxiv  

Identification and Mapping of the Replication Genes of an R Factor, R100-1, Integrated into the Chromosome of Escherichia coli K-12 [PDF]

, 1974
Masanosuke Yoshikawa
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Mapping of non-recombining regions via molecular markers

Plant, Soil and Environment, 2007
The lack of recombination in some genomic regions represents a serious obstacle in mapping studies. In this review, we describe methods that are currently used to overcome this problem.
B. Janoušek, J. Žlůvová
doaj   +1 more source

High-order chromatin architecture determines the landscape of chromosomal alterations in cancer [PDF]

arXiv, 2011
The rapid growth of cancer genome structural information provides an opportunity for a better understanding of the mutational mechanisms of genomic alterations in cancer and the forces of selection that act upon them. Here we test the evidence for two major forces, spatial chromosome structure and purifying (or negative) selection, that shape the ...
arxiv