Results 151 to 160 of about 401,380 (210)
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Current Opinion in Genetics & Development, 1995
The construction of integrated maps at all levels of resolution will facilitate determination of the DNA sequence and, ultimately, the entire gene content of the human genome. In the past two years, the need for extensive frameworks on which to anchor the maps of the human chromosomes has been emphasized. The first framework has been provided following
D R, Bently, I, Dunham
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The construction of integrated maps at all levels of resolution will facilitate determination of the DNA sequence and, ultimately, the entire gene content of the human genome. In the past two years, the need for extensive frameworks on which to anchor the maps of the human chromosomes has been emphasized. The first framework has been provided following
D R, Bently, I, Dunham
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Mapping the Phytoplasma Chromosome
2012Physical and genetic mapping of the phytoplasma chromosome can be a useful tool in a genome sequencing project in order to assemble the in silico-predicted contigs robustly. Mapping consists of four distinct steps: preparation of phytoplasma chromosomes from infected plants, single- and double-digestion of chromosomes with rare-cutting restriction ...
Malembic-Maher, Sylvie, Carle, Patricia
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Human Genetics, 1983
Starting with the male chiasma distribution for chromosome 2, a significantly better fit is obtained to lod scores for the X chromosome if terminalization of distal chiasmata is assumed. The linkage data are not consistent with a uniform distribution of chiasmata, absence of terminalization, or restriction of terminalization to the distal band.
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Starting with the male chiasma distribution for chromosome 2, a significantly better fit is obtained to lod scores for the X chromosome if terminalization of distal chiasmata is assumed. The linkage data are not consistent with a uniform distribution of chiasmata, absence of terminalization, or restriction of terminalization to the distal band.
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Molecular mapping of rice chromosomes
Theoretical and Applied Genetics, 1988We report the construction of an RFLP genetic map of rice (Oryza sativa) chromosomes. The map is comprised of 135 loci corresponding to clones selected from a PstI genomic library. This molecular map covers 1,389 cM of the rice genome and exceeds the current classical maps by more than 20%. The map was generated from F2 segregation data (50 individuals)
S R, McCouch +6 more
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2001
A central problem in cytogenetics is mapping the location of each gene. This involves determining their linear order and the physical distance and frequency of meiotic recombination between all components of each chromosome, especially the genes. The rate of progress in mapping the human chromosomes has increased rapidly.
Orlando J. Miller, Eeva Therman
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A central problem in cytogenetics is mapping the location of each gene. This involves determining their linear order and the physical distance and frequency of meiotic recombination between all components of each chromosome, especially the genes. The rate of progress in mapping the human chromosomes has increased rapidly.
Orlando J. Miller, Eeva Therman
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Chromosome Mapping with DNA Markers
Scientific American, 1988New markers called RFLP's (for restriction-fragment length polymorphisms) can indicate the location on a chromosome of a disease-causing gene and serve to identify carriers. With enough markers one can map the human chromosomes--the first step toward an ambitious goal of molecular biology: sequencing the entire human genome.
R, White, J M, Lalouel
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Linkage maps of human chromosomes
Genome, 1989Finding the chromosomal location of human genes that heretofore have been defined solely by phenotypes, in particular clinical phenotypes that are transmitted in Mendelian fashion in families, is an early and often crucial step in the process of identifying the molecular basis of a disease.
R, White +5 more
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Physical Mapping of Human Chromosomes
1992A major focus of modern molecular biology is the isolation and analysis of genes based upon associated phenotypes. The strategies for “positional cloning,” where a gene is cloned, analyzed and the basic underlying biology uncovered based upon its chromosomal map location alone, form the basis of much modern molecular genetics research and has made ...
G A, Evans, D L, McElligott
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Integrating maps of chromosome 16
Current Opinion in Genetics & Development, 1993The recently published, detailed cytogenetic-based physical map of chromosome 16 has the highest resolution of any autosomal cytogenetic map thus far constructed. The genetic map has been integrated with the cytogenetic map to facilitate the regional localization of disease genes by linkage.
J C, Mulley, G R, Sutherland
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Standard maps of chromosome 10
Annals of Human Genetics, 1990SUMMARYTo achieve consensus more exact definitions of genetical maps are required, of which standard, comprehensive and skeletal might be some. A standard genetic map gives distance from pter in centimorgans (cM), uses the international nomenclature for assigned loci, is sex‐specific, and allows as well as possible for interference and typing errors. A
Morton, Newton, Collins, Andrew
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