Results 11 to 20 of about 2,043,170 (278)

Normalization of a chromosomal contact map [PDF]

open access: yesBMC Genomics, 2012
Abstract Background Chromatin organization has been increasingly studied in relation with its important influence on DNA-related metabolic processes such as replication or regulation of gene expression. Since its original design ten years ago, capture of chromosome conformation (3C) has become an essential tool to ...
Martial Marbouty   +8 more
openaire   +7 more sources

Molecular Cytogenetics in Domestic Bovids: A Review

open access: yesAnimals, 2023
The discovery of the Robertsonian translocation (rob) involving cattle chromosomes 1 and 29 and the demonstration of its deleterious effects on fertility focused the interest of many scientific groups on using chromosome banding techniques to reveal ...
Alessandra Iannuzzi   +2 more
doaj   +1 more source

Cloning, chromosome mapping and expression pattern of porcine PLIN and M6PRBP1 genes

open access: yesGenetics Selection Evolution, 2008
The PAT proteins, named after the three PLIN/ADRP/TIP47 (PAT) proteins, PLIN for perilipin, ADRP for adipose differentiation-related protein and TIP47 for tail-interacting protein of 47 kDa, now officially named M6PRBP1 for mannose-6-phosphate receptor ...
Yang Zaiqing   +7 more
doaj   +1 more source

From Hi-C Contact Map to Three-dimensional Organization of Interphase Human Chromosomes [PDF]

open access: yesPhys. Rev. X 11, 011051 (2021), 2020
The probability of two loci, separated by a certain genome length, being in contact can be inferred using the Chromosome Conformation Capture (3C) method and related Hi-C experiments. How to go from the contact map, a matrix listing the mean contact probabilities between a large number of pairs of loci, to an ensemble of three-dimensional structures is
arxiv   +1 more source

Easy-to-Use InDel Markers for Genetic Mapping between Col-0 and Ler-0 Accessions of Arabidopsis thaliana

open access: yesPlants, 2020
Map-based gene cloning has played a key role in many genetic studies using the model plant, Arabidopsis thaliana. In the post- next generation sequencing era, identification of point mutations and their corresponding genes is increasingly becoming a ...
Takahiro Tanaka   +3 more
doaj   +1 more source

Observations on chromosome-specific sequencing for the construction of cross-species chromosome homology maps and its resolution of human:alpaca homology

open access: yesMolecular Cytogenetics, 2022
Background The history of comparative chromosome mapping is briefly reviewed, with discussion about the problem that occurs in chromosome painting when size heteromorphisms between homologues cause contamination in chromosomes sorted by flow cytometry ...
Malcolm A. Ferguson-Smith   +3 more
doaj   +1 more source

Effective Model of Loop Extrusion Predicts Chromosomal Domains [PDF]

open access: yesPhys. Rev. E 102, 032414 (2020), 2020
An active loop-extrusion mechanism is regarded as the main out--of--equilibrium mechanism responsible for the structuring of megabase-sized domains in chromosomes. We developed a model to study the dynamics of the chromosome fibre by solving the kinetic equations associated with the motion of the extruder.
arxiv   +1 more source

Mitotic-chromosome-based physical mapping of the Culex quinquefasciatus genome. [PDF]

open access: yesPLoS ONE, 2015
The genome assembly of southern house mosquito Cx. quinquefasciatus is represented by a high number of supercontigs with no order or orientation on the chromosomes.
Anastasia N Naumenko   +9 more
doaj   +1 more source

A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

open access: yesNature Communications, 2018
Long-read sequencing technologies have greatly facilitated assemblies of large eukaryotic genomes. In this paper, Oxford Nanopore sequences generated on a MinION sequencer are combined with Bionano Genomics Direct Label and Stain (DLS) optical maps to ...
S. Deschamps   +7 more
semanticscholar   +1 more source

Characterization analysis and polymorphism detection of the porcine Myd88 gene

open access: yesGenetics and Molecular Biology, 2009
The myeloid differentiation primary response protein 88 (Myd88) is an essential adaptor protein, which mediates in all Toll-like receptor (TLR) members signal transduction, except for TLR3. In this study, the 4464 bp genomic sequence of porcine Myd88 was
Xinyun Li   +6 more
doaj   +1 more source

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