Results 221 to 230 of about 2,184,990 (399)

High-resolution genome and genetic map of tetraploid Allium porrum expose pericentromeric recombination. [PDF]

open access: yesPlant Genome
Nieuwenhuis R   +9 more
europepmc   +1 more source

Dissection and fine-mapping of two QTL for grain size linked in a 460-kb region on chromosome 1 of rice [PDF]

open access: gold, 2018
Qing Dong   +7 more
openalex   +1 more source

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

open access: yesAdvanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang   +8 more
wiley   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

Genetic and biochemical analyses identify a major locus, GH-PA1, underlying pollen carotenoid accumulation and pigmentation in upland cotton. [PDF]

open access: yesJ Exp Bot
Pettit N   +9 more
europepmc   +1 more source

Chromosome mapping of the genes that control differentiation and malignancy in myeloid leukemic cells.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1977
J. Azumi, L. Sachs
semanticscholar   +1 more source

Oral Exposure to Food‐Grade Nanoparticles Poses a Risk of Alzheimer's Disease‐Like Symptoms by Triggering Autophagy Defects in Neurons

open access: yesAdvanced Science, EarlyView.
Three food‐grade nanomaterials induce dysregulated RyR‐Ca2+ signaling through epigenetic modifications. This dysregulation impairs the autophagic clearance process, ultimately leading to abnormal Aβ deposition and increase phosphorylated tau levels.
Jiaxin Shang   +7 more
wiley   +1 more source

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