Results 221 to 230 of about 414,431 (313)

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

open access: yesAdvanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha   +11 more
wiley   +1 more source

Fine mapping and candidate gene analysis of a major QTL for grain length on chromosome 5BS in bread wheat

open access: gold
Jianqi Zeng   +10 more
openalex   +1 more source

The X Chromosome in Quantitative Trait Locus Mapping

open access: green, 2006
Karl W. Broman   +5 more
openalex   +2 more sources

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

High-resolution genome and genetic map of tetraploid Allium porrum expose pericentromeric recombination. [PDF]

open access: yesPlant Genome
Nieuwenhuis R   +9 more
europepmc   +1 more source

Genomic organization and chromosomal mapping of the mouse P-cadherin gene

open access: green, 1991
Masayuki Hatta   +5 more
openalex   +2 more sources

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

QTL mapping of oat crown rust resistance in Australian fields and identification of a seedling resistance locus in oat line GS7. [PDF]

open access: yesTheor Appl Genet
Nguyen DT   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy