Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source
Development and Characterization of Wheat-<i>Thinopyrum elongatum</i> 1B-1E Translocation Lines with Fusarium Head Blight Resistance. [PDF]
Wang C +8 more
europepmc +1 more source
The X Chromosome in Quantitative Trait Locus Mapping
Karl W. Broman +5 more
openalex +2 more sources
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
High-resolution genome and genetic map of tetraploid Allium porrum expose pericentromeric recombination. [PDF]
Nieuwenhuis R +9 more
europepmc +1 more source
Genomic organization and chromosomal mapping of the mouse P-cadherin gene
Masayuki Hatta +5 more
openalex +2 more sources
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You +12 more
wiley +1 more source
QTL mapping of oat crown rust resistance in Australian fields and identification of a seedling resistance locus in oat line GS7. [PDF]
Nguyen DT +10 more
europepmc +1 more source
Mapping Quantitative Trait Loci onto Chromosome-scale Pseudomolecules in Flax
Frank M. You, Sylvie Cloutier
openalex +2 more sources

