Results 261 to 270 of about 2,184,990 (399)
A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani +20 more
wiley +1 more source
The ubiquitin protease Ubp10 suppresses the formation of translocations at interstitial telomere-like sites. [PDF]
Gonzalez DI +3 more
europepmc +1 more source
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen +22 more
wiley +1 more source
Contrasting Satellitomes in New World and African Trogons (Aves, Trogoniformes). [PDF]
Pozzobon LC +10 more
europepmc +1 more source
Report of the Fourth International Workshop on human X chromosome mapping 1993
D. Schlessinger +4 more
semanticscholar +1 more source
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui +16 more
wiley +1 more source
Elevated Soybean Seed Oil Phenotype Associated with a Single Nucleotide Polymorphism in <i>GmNFR1α</i>. [PDF]
Patibandla SV +7 more
europepmc +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source

