Results 261 to 270 of about 2,127,240 (398)

ChromInSight: Revealing DNA Double‐Strand Breaks Through Chromatin Structural Insights With an Interpretable Graph Neural Network Framework

Advanced Science, EarlyView.
DSBs are the most critical genomic lesions. Using the ChromInSight framework, It is revealed that 3D chromatin structure, rather than linear distance, shapes cluster‐scene between hub‐Nodes and DSB loci. The “spatial isolation–damage containment” hypothesis is proposed to illustrate how the genome responds to genomic damage and offer a powerful tool ...
Kang Xu, Zongyuan Yu, Canzhuang Sun, Conglin Gou, Jiangyue Zhu, Jun Wang, Xiaochen Bo, Guoxian Yu, Hao Li, Hebing Chen   +9 more
wiley   +1 more source

Chromosome-level haplotype-resolved genome assembly provides insights into the highly heterozygous genome of Italian ryegrass (Lolium multiflorum Lam.). [PDF]

Plant Genome
Chen Y, Kiesbauer J, Copetti D, Frei D, Frey JE, Grieder C, Kölliker R, Studer B.   +7 more
europepmc   +1 more source

Report of the Fourth International Workshop on human X chromosome mapping 1993

, 1993
D. Schlessinger, J. Mandel, A. Monaco, D. Nelson, H. Willard   +4 more
semanticscholar   +1 more source

Two subsets of human alphoid repetitive DNA show distinct preferential localization in the pericentromeric heterochromatin of chromosomes 13, 21 and 18 [PDF]

, 1986
Bakker, E., Cornelisse, J. L., Cremer, Thomas, Devilee, P., Hager, H. D., Pearson, P., Scholl, Hans Peter, Slagboom, P., Stevenson, A. F. G.   +8 more
core  

Draper‐ATG3 Interaction Positively Regulates Autophagy to Mediate Silk Gland Degradation in Bombyx mori

Advanced Science, EarlyView.
Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou, Yuhan Luo, Yue Jin, Wenhui Jing, Yuxin Huang, Yanting Liang, Yinghui Li, Zhihua Hao, Yusong Xu, Huabing Wang   +9 more
wiley   +1 more source

Opinion: Why Sex-Based Genomic Differentiation Should Not Be Overlooked in Population Genetics. [PDF]

Mol Ecol
Chen YC, Vellnow N, Wilcox JJS, Javaheri Tehrani S, Gossmann TI.   +4 more
europepmc   +1 more source

Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre‐ and Post‐Implantation Epigenetic Barriers

Advanced Science, EarlyView.
Mammalian cloning via SCNT is limited by several epigenetic barriers. Kdm4d/Kdm5b overexpression plus TSA treatment overcomes epigenetic barriers during pre‐implantation development, while tetraploid complementation replaces defective extraembryonic lineages to bypass H3K27me3 imprinting loss to overcome epigenetic barriers in post‐implantation ...
Yamei Li, Shiyu Sun, Yuting Xu, Jixiang Zhang, Yi Du, Yaxin Cao, Zhaodi Liao, Yali Xie, Xinyan Bian, Jiantao Huang, Meijiao Wang, Zhen Liu, Qiang Sun, Falong Lu   +13 more
wiley   +1 more source

A chickpea MAGIC population to dissect the genetics of complex traits. [PDF]

Plant Genome
Akinlade OJ, Robinson H, Kang Y, Thudi M, Samineni S, Gaur P, Smith MR, Voss-Fels KP, Costilla R, Varshney RK, Dinglasan E, Hickey LT.   +11 more
europepmc   +1 more source

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples

Advanced Science, EarlyView.
FemXpress is a computational tool that leverages X‐linked single nucleotide polymorphisms (SNPs) to group cells by the origin of the inactivated X chromosome in female single‐cell RNA sequencing (scRNA‐Seq) data. It demonstrates strong performance on both simulated and real datasets without requiring parental genomic information, and can also identify ...
Xin Wang, Yingke Ma, Fan Li, Wentao Cui, Tianshi Pan, Siqi Wang, Sinan Ma, Qingtong Shan, Chao Liu, Yukai Wang, Ying Zhang, Yuanchun Zhou, Wei Li, Pengfei Wang, Qi Zhou, Guihai Feng   +15 more
wiley   +1 more source

Gut length evolved under sexual conflict in Lake Malawi cichlids. [PDF]

Genetics
Carmona Baez A, Ciccotto PJ, Moore EC, Peterson EN, Lamm MS, Roberts NB, Coyle KP, Barker MK, Dickson E, Cass AN, Pereira GS, Zeng ZB, Guerrero RF, Roberts RB.   +13 more
europepmc   +1 more source