Molecular Cytogenetics, 2022 Background The history of comparative chromosome mapping is briefly reviewed, with discussion about the problem that occurs in chromosome painting when size heteromorphisms between homologues cause contamination in chromosomes sorted by flow cytometry ...
Malcolm A. Ferguson-Smith +3 more
doaj +1 more source
A genome-wide search for risk genes using homozygosity mapping and microarrays with 1,494 single-nucleotide polymorphisms in 22 eastern Cuban families with bipolar disorder [PDF]
, 2005 Homozygosity mapping is a very powerful method for finding rare recessive disease genes in monogenic disorders and may also be useful for locating risk genes in complex disorders, late onset disorders where parents often are not available, and for rare ...
American Psychiatric Association +21 more
core +1 more source
Mitotic-chromosome-based physical mapping of the Culex quinquefasciatus genome. [PDF]
PLoS ONE, 2015 The genome assembly of southern house mosquito Cx. quinquefasciatus is represented by a high number of supercontigs with no order or orientation on the chromosomes.
Anastasia N Naumenko +9 more
doaj +1 more source
A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
Nature Communications, 2018 Long-read sequencing technologies have greatly facilitated assemblies of large eukaryotic genomes. In this paper, Oxford Nanopore sequences generated on a MinION sequencer are combined with Bionano Genomics Direct Label and Stain (DLS) optical maps to ...
S. Deschamps +7 more
semanticscholar +1 more source
Fluorescence in situ hybridization of YAC clones after Alu-PCR amplification [PDF]
, 1992 Alu-PCR protocols were optimized for the generation of human DNA probes from yeast strains containing yeast artificial chromosomes (YACs) with human inserts between 100 and 800 kb in size.
Brooks-Wilson +15 more
core +1 more source
Characterization analysis and polymorphism detection of the porcine Myd88 gene
Genetics and Molecular Biology, 2009 The myeloid differentiation primary response protein 88 (Myd88) is an essential adaptor protein, which mediates in all Toll-like receptor (TLR) members signal transduction, except for TLR3. In this study, the 4464 bp genomic sequence of porcine Myd88 was
Xinyun Li +6 more
doaj +1 more source
Multiple QTL for horticultural traits and quantitative resistance to Phytophthora infestans linked on Solanum habrochaites chromosome 11. [PDF]
, 2014 Previously, a Phytophthora infestans resistance QTL from Solanum habrochaites chromosome 11 was introgressed into cultivated tomato (S. lycopersicum). Fine mapping of this resistance QTL using near-isogenic lines (NILs) revealed some co-located QTL with ...
Haggard, J Erron +2 more
core +1 more source
The Journal of Poultry Science, 2014 To better understand the process of karyotype evolution in Galloanserae (Galliformes and Anseriformes), we performed comparative chromosome painting with chicken chromosome-specific DNA probes and FISH mapping of the 18S-28S ribosomal RNA (rRNA) genes ...
Fhamida B. Islam +6 more
doaj +1 more source
Genome Research, 2017 Long-read sequencing can overcome the weaknesses of short reads in the assembly of eukaryotic genomes; however, at present additional scaffolding is needed to achieve chromosome-level assemblies.
Wen-Biao Jiao +17 more
semanticscholar +1 more source
A framework for gene mapping in wheat demonstrated using the Yr7 yellow rust resistance gene [PDF]
, 2020 We used three approaches to map the yellow rust resistance gene Yr7 and identify associated SNPs in wheat. First, we used a traditional QTL mapping approach using a double haploid (DH) population and mapped Yr7 to a low-recombination region of chromosome
Bansept-Basler, Pauline +4 more
core +3 more sources