Results 321 to 330 of about 2,184,990 (399)
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Mapping the Phytoplasma Chromosome
2012Physical and genetic mapping of the phytoplasma chromosome can be a useful tool in a genome sequencing project in order to assemble the in silico-predicted contigs robustly. Mapping consists of four distinct steps: preparation of phytoplasma chromosomes from infected plants, single- and double-digestion of chromosomes with rare-cutting restriction ...
Malembic-Maher, Sylvie, Carle, Patricia
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An integrated map of chromosome 9
Annals of Human Genetics, 1995SUMMARYAn integrated map of 211 loci on chromosome 9 is presented for which 198 loci have genetic locations. The results of the analysis indicate very strong interference for the chromosome and positional variations in recombination rates, most extreme in the male map where there is an excess of recombination near the p telomere and a marked ...
COLLINS A +3 more
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Molecular mapping of rice chromosomes
Theoretical and Applied Genetics, 1988We report the construction of an RFLP genetic map of rice (Oryza sativa) chromosomes. The map is comprised of 135 loci corresponding to clones selected from a PstI genomic library. This molecular map covers 1,389 cM of the rice genome and exceeds the current classical maps by more than 20%. The map was generated from F2 segregation data (50 individuals)
S R, McCouch +6 more
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Chromosome Mapping with DNA Markers
Scientific American, 1988New markers called RFLP's (for restriction-fragment length polymorphisms) can indicate the location on a chromosome of a disease-causing gene and serve to identify carriers. With enough markers one can map the human chromosomes--the first step toward an ambitious goal of molecular biology: sequencing the entire human genome.
R, White, J M, Lalouel
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Chromosome maps of man and mouse
Clinical Genetics, 1981Graphical displays and listings are presented showing the chromosomal locations of the loci referred to in the Edinburgh Human Gene Mapping Conference (1979), those regarded as homologous between mouse and man, and some others used in linkage studies of chromosomal rearrangements in the mouse.
T P, Dalton +6 more
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Physical Mapping of Human Chromosomes
1992A major focus of modern molecular biology is the isolation and analysis of genes based upon associated phenotypes. The strategies for “positional cloning,” where a gene is cloned, analyzed and the basic underlying biology uncovered based upon its chromosomal map location alone, form the basis of much modern molecular genetics research and has made ...
G A, Evans, D L, McElligott
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Annals of Human Genetics, 1984
SummaryThe genetic map of chromosome 1 reported by Keats, Morton & Rao (1981) has been updated using recent recombination data and regional assignments from the Galton Laboratory (King, 1982a) and from the current literature. A maximum likelihood mapping technique using pairwise recombination data without a chiasma map was developed, based on the ...
S L, Sherman +3 more
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SummaryThe genetic map of chromosome 1 reported by Keats, Morton & Rao (1981) has been updated using recent recombination data and regional assignments from the Galton Laboratory (King, 1982a) and from the current literature. A maximum likelihood mapping technique using pairwise recombination data without a chiasma map was developed, based on the ...
S L, Sherman +3 more
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Chromosome mapping of cell membrane antigens expressed on activated B cells
European Journal of Immunology, 1985Hybrids formed by fusion of either human acute lymphoblastic or chronic lymphocy‐tic leukemia cells and the mouse myeloma P3.X63.Ag81653 have been used to show that the expression of two cell surface antigens, Bp37 and p76, associated with B cell ...
F. Katz +5 more
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Linkage maps of human chromosomes
Genome, 1989Finding the chromosomal location of human genes that heretofore have been defined solely by phenotypes, in particular clinical phenotypes that are transmitted in Mendelian fashion in families, is an early and often crucial step in the process of identifying the molecular basis of a disease.
R, White +5 more
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Integrating maps of chromosome 16
Current Opinion in Genetics & Development, 1993The recently published, detailed cytogenetic-based physical map of chromosome 16 has the highest resolution of any autosomal cytogenetic map thus far constructed. The genetic map has been integrated with the cytogenetic map to facilitate the regional localization of disease genes by linkage.
J C, Mulley, G R, Sutherland
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