Results 31 to 40 of about 194,576 (309)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

QTL analysis on rice genotypes adapted to acid sulfate soils in the Mekong river delta, Vietnam

open access: yesVietnam Journal of Science, Technology and Engineering, 2017
Three target points in acid sulfate soils have been identified as: 1) Aluminum (Al) toxicity; 2) Iron (Fe) toxicity; 3) Phosphorous (P) deficiency; and 4) Droughts at the seedling stage.
Chi Buu Bui, Thi Lang Nguyen
doaj   +1 more source

Identification of the sex-determining locus in grass puffer (Takifugu niphobles) provides evidence for sex-chromosome turnover in a subset of Takifugu species. [PDF]

open access: yesPLoS ONE, 2018
There is increasing evidence for frequent turnover in sex chromosomes in vertebrates. Yet experimental systems suitable for tracing the detailed process of turnover are rare.
Risa Ieda   +11 more
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

The Regulation of Anthocyanin Synthesis in the Wheat Pericarp

open access: yesMolecules, 2014
Bread wheat producing grain in which the pericarp is purple is considered to be a useful source of dietary anthocyanins. The trait is under the control of the Pp-1 homoealleles (mapping to each of the group 7 chromosomes) and Pp3 (on chromosome 2A). Here,
Olesya Y. Shoeva   +2 more
doaj   +1 more source

The construction of chromosome maps

open access: yesExperimental Biology and Medicine, 1919
The accuracy with which a chromosome map may be constructed depends upon several conditions. (1) The mutant characters employed should be carefully restricted to those cleanly separable both from the wild type and from each other, and whose viability is practically the same as that of the wild type.
Thomas Hunt Morgan, Calvin B. Bridges
openaire   +2 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2

open access: yesJournal of Lipid Research, 2000
Dietary cholesterol is known to raise total and low density lipoprotein cholesterol concentrations in humans and experimental animals, but the response among individuals varies greatly.
Aram Mouzeyan   +9 more
doaj  

An isochore map of human chromosomes [PDF]

open access: yesGenome Research, 2006
Isochores are large DNA segments (≫300 kb on average) that are characterized by an internal variation in GC well below the full variation seen in the mammalian genome. Precisely defining in terms of size and composition as well as mapping the isochores on human chromosomes have, however, remained largely unsolved problems.
Giorgio Bernardi   +3 more
openaire   +3 more sources

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