Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations [PDF]
, 2005 Gene-poor human chromosomes are reproducibly found at the nuclear periphery in proliferating cells. There are a number of inner nuclear envelope proteins that may have roles in chromosome location and anchorage, e.g. emerin and A-type lamins.
Bridger, JM +3 more
core +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Chromosome numbers, meiotic behavior and pollen fertility in a collection of Paspalum nicorae Parodi accessions [PDF]
Crop Breeding and Applied Biotechnology, 2008 Chromosome number, meiotic behavior and pollen viability were evaluated in a collection of 53 Paspalumnicorae Parodi accessions, which are part of a breeding project of the species.
Camila Aparecida de Oliveira dos Reis +2 more
doaj
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Cytogenetics of Hypericum caprifoliatum Cham. & Schltdl. (Clusiaceae) populations and other species of the genus [PDF]
Crop Breeding and Applied Biotechnology, 2008 Chromosome numbers and meiotic behavior are presented for the first time for Hypericum caprifoliatum(2n=48), H. cf carinatum (2n=48) and H. polyanthemum (2n= 32) and confirmed the H. perforatum (2n=32) number.Chromosomes are very small (ca.
Danielle Almeida +3 more
doaj
Increased heterozygosity and allele variants are seen in Texel compared to Suffolk sheep [PDF]
, 2004 In this study, the Suffolk and Texel sheep breeds were compared for microsatellite marker heterozygosity throughout seven chromosomal regions in the sheep genome.
A Farid +48 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
تاکسونومی و بیوسیستماتیک, 2012 A total of 58 accessions of Eremopoa persica and E. songarica belongigng to the family Poaceae and tribe Festuceae (Poacea) were morphologically studied.
Sorour Rahmanian +1 more
doaj
Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
, 2014 The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core +2 more sources
Predicting survival of cancer patients by chromosomal copy number heterogeneity [PDF]
, 2021 Tom van den Bosch +3 more
openalex +1 more source