Results 101 to 110 of about 803,632 (356)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Chromosome Number of Cardamine pratensis [PDF]

Nature, 1948
I NOTICE with interest Dr. Howard‘s records of chromosome counts of 2n = 56 for several plants of Cardamine pratensis growing in damp places1. I have been working on British plants of this species for the last two years, with the help and guidance of Dr. K. B.
openaire   +5 more sources

Polygonatum cyrtonema var. gutianshanicum——A new variety of Polygonatum cyrtonema and comparative studies on it and the similar species

浙江大学学报. 农业与生命科学版, 2002
In this paper, a new variety of Polygonatum cyrtonema——P. cyrtonema var. guitanshancum was discribed. Karyotypical and morphological studies of it and the similar specics were also giv en.
JIN Xiao feng, QIU Ying-xiong, DING Bing-yang   +2 more
doaj   +1 more source

Chromosome-length genome assemblies and cytogenomic analyses of pangolins reveal remarkable chromosome counts and plasticity

, 2023
We report the first chromosome-length genome assemblies for three species in the mammalian order Pholidota: the white-bellied, Chinese, and Sunda pangolins.
Lim, Norman (Norman T-Lon), Janecka, Jan E., Stephen J. O’Brien, Harrigan, Ryan J., Marlys L. Houck, O'Brien, Stephen J., Gentry, Jordan, Alexander Graphodatsky, Luo, Shu-Jin, Jason S. C. Chin, Ginger Sturgeon, Guerra, Vanessa, Chin, Jason S. C., Arina Omer, Kaemmerer, Kenneth, Olga Dudchenko, Lieberman Aiden, Erez, Gaspard, Joseph, Coke, Rob L., Lim, Norman T.-L., Aiden, Erez Lieberman, Koepfli, Klaus-Peter, Norman T.-L. Lim, Shu-Jin Luo, Jan E. Janecka, Alicia Hahn, Dudchenko, Olga, Beklemisheva, Violetta R., Hahn, Alicia, O’Brien, Stephen J., Houck, Marlys L., Jordan Gentry, Mark McDonough, Isabel Garcia-Treviño, Janecka, Jan. E., Julie A. Fronczek, Beklemisheva, Violetta, Vanessa Guerra, Rob L. Coke, Kliver, Sergei, Sturgeon, Ginger, Hains, Taylor, Misuraca, Ann C., Tamazian, Gaik, McDonough, Mark, Jen Tinsman, Garcia-Treviño, Isabel, Tinsman, Jen, Violetta Beklemisheva, Joseph Gaspard, Klaus-Peter Koepfli, Fronczek, Julie A., Thomas B. Smith, Weisz, David, Gaik Tamazian, Sergei Kliver, Erez Lieberman Aiden, Kenneth Kaemmerer, Khan, Ruqayya, Ann C. Misuraca, Perelman, Polina L., David Weisz, Ruqayya Khan, Suellen J. Charter, Ryan J. Harrigan, Polina L. Perelman, Graphodatsky, Alexander, Smith, Thomas B., Taylor Hains, Omer, Arina, Charter, Suellen J.   +70 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The effect of genes on A and B chromosomes of a number of Triticinae on meiotic behaviour in Triticum aestivum and its hybrids with related species

, 1979
Results obtained and hypotheses that have been put forward to integrate them, are summarized in this section.1. Studies of chromosome association in F 1 hybrids Triticum aestivum X Secale cereale with and without chromosome 5B and in the presence or in ...
Viegas, W.S.
core  

Bidirectional transcription of a novel chimeric gene mapping to mouse chromosome Yq [PDF]

, 2007
Background The male-specific region of the mouse Y chromosome long arm (MSYq) contains three known highly multi-copy X-Y homologous gene families, Ssty1/2, Sly and Asty.
Nabeel A Affara, Ellis, Peter J.I., Ellis Peter JI, Clemente, Emily J., Peter JI Ellis, Ferguson Lydia, Emily J Clemente, Clemente Emily J, Affara Nabeel A, Ferguson, Lydia, Affara, Nabeel A., Lydia Ferguson   +11 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Chromosome number and karyotype of the endangered Amazonian woody Centrolobium paraense Tul. species [PDF]

Crop Breeding and Applied Biotechnology, 2009
Centrolobium paraense Tul., popularly known in Brazil as “pau-rainha”, is a species with a high timberpotential, presently endangered due to deforestation of the Amazonian region and indiscriminate wood extraction.
Nair Dahmer, Maria Teresa Schifino Wittmann, Paulo Emilio Kaminski   +2 more
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source