Results 81 to 90 of about 803,632 (356)
A family case of fertile human 45,X,psu dic(15;Y) males [PDF]
We report on a familial case including four male probands from three generations with a 45,X,psu dic(15;Y)(p11.2;q12) karyotype. 45,X is usually associated with a female phenotype and only rarely with maleness, due to translocation of small Y chromosomal
P.M. Gopinath +17 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Role of the Number of Microtubules in Chromosome Segregation during Cell Division [PDF]
Faithful segregation of genetic material during cell division requires alignment of chromosomes between two spindle poles and attachment of their kinetochores to each of the poles.
Z. Bertalan +3 more
semanticscholar +1 more source
Chromosome number and satellited chromosome morphology of eleven species of Arachis (Leguminosae)
The chromosome number was determined in eleven recently-described species of Arachís belonging to five different axonomic sections. Two new species of section Arachís, A. Gregoryí and A.
Andréa del Pilar De Souza Penaloza +1 more
doaj
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Comparative genomics reveals the dynamics of chromosome evolution in Lepidoptera
Chromosomes are a central unit of genome organization. One-tenth of all described species on Earth are butterflies and moths, the Lepidoptera, which generally possess 31 chromosomes.
C. Wright +4 more
semanticscholar +1 more source
Integrating Hi-C links with assembly graphs for chromosome-scale assembly
Motivation Long-read sequencing and novel long-range assays have revolutionized de novo genome assembly by automating the reconstruction of reference-quality genomes.
Jay Ghurye +7 more
semanticscholar +1 more source
MEIOSIS: HOW TO HALVE THE CHROMOSOME NUMBER
The notion of meiosis has been changed and refined for over a century since the discovery of this complicated way of cell division. Its success depends on precise time and space orchestration of many processes, such as chromosome replication, packaging ...
A. A. Torgasheva
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Chromosome Number in the Sequoias
cycads, screw pines, palms, orchids, figs, ebonies, the gorgeous Amlerstia, and many other tropical trees grow luxuriantly. All in all, Jamaica probably offers the botanist as great a variety of tropical conditions within a day's walk of Cinchona and a ...
T. H. Goodspeed, M. P. Crane
semanticscholar +1 more source

