Results 91 to 100 of about 12,452,954 (349)

Metaphase Configurations in Drosophila: A Comparison of Endemic Hawaiian Species and Non-Endemic Species [PDF]

, 1976
The metaphase configurations of 400 strains from 63 species of Hawaiian Drosophila were determined from squash preparations of larval brain tissue or spermatogenic cells from adult testes.
Clayton, Frances E.
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The structure, function and evolution of a complete human chromosome 8

Nature, 2020
The complete assembly of each human chromosome is essential for understanding human biology and evolution1,2. Here we use complementary long-read sequencing technologies to complete the linear assembly of human chromosome 8.
Glennis A. Logsdon, Mitchell R. Vollger, Pinghsun Hsieh, Yafei Mao, M. Liskovykh, S. Koren, S. Nurk, L. Mercuri, Philip C. Dishuck, A. Rhie, L. D. de Lima, T. Dvorkina, David Porubsky, William T. Harvey, Alla Mikheenko, Andrey V. Bzikadze, Milinn Kremitzki, Tina A. Graves-Lindsay, Chirag Jain, Kendra Hoekzema, S. Murali, Katherine M. Munson, Carl A. Baker, Melanie Sorensen, Alexandra M. Lewis, U. Surti, J. Gerton, V. Larionov, M. Ventura, K. Miga, A. Phillippy, E. Eichler   +31 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Chromosome number and satellited chromosome morphology of eleven species of Arachis (Leguminosae)

Bonplandia, 2005
The chromosome number was determined in eleven recently-described species of Arachís belonging to five different axonomic sections.  Two new species  of section  Arachís, A. Gregoryí and A.
Andréa del Pilar De Souza Penaloza, José Fransisco Montenegro Valls   +1 more
doaj  

Massive gene amplification on a recently formed Drosophila Y chromosome. [PDF]

, 2019
Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
Bachtrog, Doris, Bracewell, Ryan, Mahajan, Shivani   +2 more
core   +1 more source

Comparative genomics reveals the dynamics of chromosome evolution in Lepidoptera

Nature Ecology & Evolution
Chromosomes are a central unit of genome organization. One-tenth of all described species on Earth are butterflies and moths, the Lepidoptera, which generally possess 31 chromosomes.
C. Wright, Lewis Stevens, Alexander Mackintosh, M. Lawniczak, Mark Blaxter   +4 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

MEIOSIS: HOW TO HALVE THE CHROMOSOME NUMBER

Вавиловский журнал генетики и селекции, 2014
The notion of meiosis has been changed and refined for over a century since the discovery of this complicated way of cell division. Its success depends on precise time and space orchestration of many processes, such as chromosome replication, packaging ...
A. A. Torgasheva
doaj