Results 71 to 80 of about 759,542 (265)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
تاکسونومی و بیوسیستماتیک, 2012 A total of 58 accessions of Eremopoa persica and E. songarica belongigng to the family Poaceae and tribe Festuceae (Poacea) were morphologically studied.
Sorour Rahmanian +1 more
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Karyological studies and taxonomic notes for some representatives of Crocus biflorus aggregate (Iridaceae) [PDF]
Comprehensive Plant BiologyCrocus biflorus aggregate is the most complex group of the genus in terms of its taxonomy and cytology. In the present study, a karyological analysis of six Crocus species in the C. biflorus aggregate (i.e. C. adanensis, C. aerius, C.
Pepy Bareka +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Acta Botânica Brasílica, 2008 Plântulas de Cybistax antisyphilitica (ipê-verde), espécie arbórea que ocorre no Estado de São Paulo, Brasil, foram estudadas morfoanatomicamente e citogeneticamente. As plântulas são eudicotiledôneas, fanerocotiledonares e epigéias.
Flavia Aparecida Ortolani +4 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Taxonomical identity of Sarcocornia fruticosa and S. hispanica in the Iberian Peninsula
Anales del Jardín Botánico de Madrid, 2014 The recent description of Sarcocornia hispanica, from SE Iberian Peninsula evidences the notable morphological complexity of this genus. This species is quite close to S. fruticosa, as they both show an erect habit and lack of rooting stems.
Ana Guilló +4 more
doaj +1 more source
Chromosome numbers of Cruciferae. II
Contributions from the Gray Herbarium of Harvard University, 1971 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Rollins, Reed C. (Reed Clark) +1 more
openaire +1 more source