Results 61 to 70 of about 759,542 (265)
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Análises cariotípicas são importantes ferramentas de auxílio aos estudos de relações taxonômicas dentro dos grupos vegetais. Espécies arbóreas nativas encontradas no cerrado brasileiro têm sido pouco analisadas do ponto de vista citogenético e ...
Flavia Aparecida Ortolani +3 more
doaj +1 more source
Premise Counting chromosomes is a fundamental botanical technique, yet it is often intimidating and increasingly sidestepped. Once mastered, the basic protocol can be applied to a broad range of taxa and research questions.
Michael D. Windham +5 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
In this paper, a new variety of Polygonatum cyrtonema——P. cyrtonema var. guitanshancum was discribed. Karyotypical and morphological studies of it and the similar specics were also giv en.
JIN Xiao feng +2 more
doaj +1 more source
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Chromosome number and karyotype of the endangered Amazonian woody Centrolobium paraense Tul. species [PDF]
Centrolobium paraense Tul., popularly known in Brazil as “pau-rainha”, is a species with a high timberpotential, presently endangered due to deforestation of the Amazonian region and indiscriminate wood extraction.
Nair Dahmer +2 more
doaj

