Results 131 to 140 of about 821,591 (309)

Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]

open access: yes, 2020
Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.
Axelrod, Joshua   +14 more
core  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Citogenética de Piper hispidinervum e Piper aduncum Cytogenetics of Piper hispidinervum and Piper aduncum

open access: yesPesquisa Agropecuária Brasileira, 2007
O objetivo deste trabalho foi detectar diferenças entre duas espécies de pimenta-longa por meio de análise de cariótipos. Foram analisados cinco acessos de Piper hispidinervum (Piperaceae) C. DC. e Piper aduncum L.
Juliane Dornellas Nunes   +3 more
doaj   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Malpighiaceae: correlations between habit, fruit type and basic chromosome number Malpighiaceae: correlações entre hábito, tipo de fruto e número cromossômico básico

open access: yesActa Botânica Brasílica, 2003
The family Malpighiaceae presents species with different habits, fruit types and cytological characters. Climbers are considered the most derived habit, followed, respectively, by the shrubby and arboreal ones. The present study examines the relationship
Ricardo A. Lombello   +1 more
doaj   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Morphometric Variations Between Triploid and Diploid Clarias gariepinus (Burchell, 1822)

open access: yesCroatian Journal of Fisheries, 2017
Several scientific methods have been described in the identification of triploid fish. However, many of these methods are not applicable for routine management purposes due to their complexity and cost.
Normala Jalil   +6 more
doaj   +1 more source

Karyotypes of six previously unstudied European mealybugs (Homoptera: Pseudococcidae)

open access: yesComparative Cytogenetics, 2010
Phenacoccus peruvianus Granada de Willink, 2007, Ph. prope avenae Borchsenius, 1949, Ph. hordei (Lindeman, 1886), Вalanococcus boratynskii Williams, 1962, Trionymus  radicum (Newstead, 1895), Rhizoecus halophilus (Hardy, 1868) were studied ...
Ilya Gavrilov-Zimin, I Trapeznikova
doaj   +1 more source

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