Results 151 to 160 of about 803,632 (356)

The Chromosome Number and rDNA Loci Evolution in Onobrychis (Fabaceae). [PDF]

open access: yesInt J Mol Sci, 2022
Yucel G   +5 more
europepmc   +1 more source

Statistical mechanics of genome regulation: the case of X chromosome inactivation

open access: yes, 2010
The aim of my PhD research project was to discover the mechanisms behind X Chromosome Inactivation (XCI) one of the most intriguing issues of the current mammalian Biology.
Scialdone, Antonio
core  

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

Chromosome Number and Genome Size Evolution in Brasolia and Sobralia (Sobralieae, Orchidaceae). [PDF]

open access: yesInt J Mol Sci, 2022
Baranow P   +8 more
europepmc   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Cytogenetics of Chilean angiosperms: Advances and prospects Citogenética de angiospermas chilenas: Avances y proyecciones

open access: yesRevista Chilena de Historia Natural, 2012
Cytogenetic data on Chilean angiosperms have been reported since at least eight decades ago; however, much of this information is disperse in diverse sources and is not readily available as a comprehensive document that allows having a general vision on ...
PEDRO JARA-SEGUEL, JONATHAN URRUTIA
doaj  

Reproductive system of Eriocnema fulva Naudin (Melastomataceae), an endemic species of Minas Gerais state, SE Brazil

open access: yesBrazilian Journal of Biology
Eriocnema fulva Naudin is a perennial herb, endemic to Minas Gerais state, SE Brazil, found on humid, shaded rocky riverbanks in montane semideciduous seasonal forests.
PM. Andrade   +2 more
doaj   +1 more source

Chromosome territory position and active relocation in normal and hutchinson-gilford progeria fibroblasts [PDF]

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Radial chromosome positioning in interphase nuclei is non-random and can alter according to developmental, differentiation, proliferation or disease status.
Mehta, Ishita Shailesh
core  

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