Results 161 to 170 of about 803,632 (356)

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Are chromosome number and genome size associated with habit and environmental niche variables? Insights from the Neotropical orchids. [PDF]

Ann Bot, 2022
Moraes AP, Engel TBJ, Forni-Martins ER, de Barros F, Felix LP, Cabral JS.   +5 more
europepmc   +1 more source

Functional and molecular effects of chromosome 21 trisomy

, 2010
Down Syndrome (DS) is the most frequent autosomal aneuploidy that is compatible with post-natal life. The DS phenotype has been attributed to overexpression of chromosome 21 (Hsa21) genes.
Izzo, Antonella
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Total DNA Content and Ploidy Levels in Linnaeoideae with a Focus on Abelia

Journal of the American Society for Horticultural Science
The Linnaeoideae subfamily was created in Caprifoliaceae to represent the close relationship among the monophyletic genera Abelia, Diabelia, Dipelta, Kolkwitzia, Linnaea, and Vesalea.
Leynar Leyton Naranjo, Carol D. Robacker
doaj   +1 more source

Chromosome Number, Ploidy Level, and Nuclear DNA Content in 23 Species of Echeveria (Crassulaceae). [PDF]

Genes (Basel), 2021
Palomino G, Martínez-Ramón J, Cepeda-Cornejo V, Ladd-Otero M, Romero P, Reyes-Santiago J.   +5 more
europepmc   +1 more source

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

, 2014
Canine hemangiosarcoma is a highly aggressive vascular neoplasm associated with extensive clinical and anatomical heterogeneity and a grave prognosis. Comprehensive molecular characterization of hemangiosarcoma may identify novel therapeutic targets and ...
Borst, Luke, Modiano, Jaime F., Breen, Matthew, Rotroff, Daniel, Motsinger-Reif, Alison, Thomas, Rachael, Lindblad-Toh, Kerstin,   +6 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Cytogenetic characterization of Angelonia integerrima Sprengel, a native species with ornamental potential

Crop Breeding and Applied Biotechnology, 2019
Angelonia integerrima Sprengel is a native species of the state of Mato Grosso do Sul and the Southern region (Paraná, Santa Catarina and Rio Grande do Sul) of Brazil, with features such as an unusual appearance and color of the flowers, indicating an ...
Carine Simioni, Marília Tedesco, Aquélis Armiliato Emer, Mara Cíntia Winhelmann, Eduarda Demari Avrella, Karine Cristina Krycki, Gilmar Schafer   +6 more
doaj  

Genome Size and Chromosome Number Evaluation of Astragalus L. sect. Hymenostegis Bunge (Fabaceae). [PDF]

Plants (Basel), 2022
Bagheri A, Akhavan Roofigar A, Nemati Z, Blattner FR.   +3 more
europepmc   +1 more source