Results 201 to 210 of about 402,124 (270)
Advanced Science, EarlyView.PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal +23 more
wiley +1 more source
Chromosome number and its significance in Batis maritima (Bataceae)
, 1976 Peter Goldblatt
openalex +2 more sources
Advanced Science, EarlyView.By combining snRNA‐seq and bulk RNA‐seq, this study identified key hepatocyte subtypes, genes, and pathways in HCC. It established a Quantile Distribution Model, providing potential targets for HCC diagnosis and treatment. It categorized HCC into metabolic, inflammatory, and matrix classes, each with sensitive drugs identified.
Huanhou Su +18 more
wiley +1 more source
Genomic Insights into Post‐Domestication Expansion and Selection of Body Size in Ponies
Advanced Science, EarlyView.The authors’ research delves into the history of ponies by assembling a pony genome and integrating horse genomes. This unveils genetic connections between Asian and European pony breeds. Cis‐regulatory elements of key genes impacting body size are also identified.
Xingzheng Li +23 more
wiley +1 more source
The Chromosome Numbers and the Multiple Chromosomes in Gryllinae
Proceedings of the Imperial Academy, 1926 openaire +3 more sources
Advanced Science, EarlyView.Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du +8 more
wiley +1 more source
Chromosome number and morphological characteristics of some Andropogoneae of Pakistan.
, 1979 Shamim A. Faruqi +2 more
openalex +2 more sources
Advanced Science, EarlyView.Cryo‐EM reveals a closed 17‐subunit LH ring encircling the RC‐LH1 complex in Dinoroseobacter shibae, featuring a novel helix‐turn‐helix subunit bridging RC and LH. Mg2⁺/Ca2⁺ stabilizes the complex, while periplasmic Cyt c₂ mediates electron transfer via a tri‐heme Cyt to the special pair of bacteriochlorophylls. Insights into energy/electron efficiency
Weiwei Wang +12 more
wiley +1 more source