Results 171 to 180 of about 405,684 (326)

Mouse NTCP (Na+-taurocholate cotransporting polypeptide) gene: Exon/iintron organization, promoter structure and chromosomal localization [PDF]

, 1998
Meenakshisundaram Ananthanarayanan, Tamara Potseleuva, Richard M. Green, Frederick J. Suchy   +3 more
openalex   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Per-nucleus crossover covariation is regulated by chromosome organization. [PDF]

iScience, 2022
Fan C, Yang X, Nie H, Wang S, Zhang L.
europepmc   +1 more source

Chromosome Organization by Loop Extrusion and Phase Separation [PDF]

, 2019
Leonid A. Mirny
openalex   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

Newfound features of meiotic chromosome organization that promote efficient congression and segregation in Caenorhabditis elegans oocytes. [PDF]

Mol Biol Cell, 2022
Horton HH, Divekar NS, Wignall SM.
europepmc   +1 more source

Involvement of condensin-directed gene associations in the organization and regulation of chromosome territories during the cell cycle [PDF]

, 2015
Osamu Iwasaki, Christopher J. Corcoran, Ken-ichi Noma   +2 more
openalex   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

Advanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li, Dong Zhang, Eryu Peng, Shijun Shen, Hamid Alinejad‐Rokny, Yao Liu, Junke Zheng, Cizhong Jiang, Youqiong Ye   +8 more
wiley   +1 more source

A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes. [PDF]

Chromosoma, 2023
Nieken KJ, O'Brien K, McDonnell A, Zhaunova L, Ohkura H.   +4 more
europepmc   +1 more source

How Entropic Forces can Drive Chromosome Organization [PDF]

, 2011
Bela M. Mulder
openalex   +1 more source