Results 41 to 50 of about 4,074,715 (354)

Chromosome Organization: Original Condensins [PDF]

open access: yesCurrent Biology, 2014
Two new studies reveal the main actors involved in the resolution and segregation of newly replicated origins in bacteria. These results have important implications for our understanding of the mechanisms involved in precisely coordinating chromosome organization, segregation and replication.
Diego I. Cattoni   +2 more
openaire   +3 more sources

Control of Smc Coiled Coil Architecture by the ATPase Heads Facilitates Targeting to Chromosomal ParB/parS and Release onto Flanking DNA

open access: yesCell Reports, 2016
Smc/ScpAB promotes chromosome segregation in prokaryotes, presumably by compacting and resolving nascent sister chromosomes. The underlying mechanisms, however, are poorly understood.
Anita Minnen   +5 more
doaj   +1 more source

Organization of the Chromosome

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1956
The observational and experimental results presented here constitute another chapter in a continuing research program that is directed toward an understanding of patterns of organization of chromosomal materials. Evidence has been sought over the years at various levels of analysis, beginning with descriptive cytology, progressing into the areas of ...
Margaret R. McDonald   +1 more
openaire   +3 more sources

Entropic organization of interphase chromosomes [PDF]

open access: yesJournal of Cell Biology, 2009
Chromosomes are not distributed randomly in nuclei. Appropriate positioning can activate (or repress) genes by bringing them closer to active (or inactive) compartments like euchromatin (or heterochromatin), and this is usually assumed to be driven by specific local forces (e.g., involving H bonds between nucleosomes or between nucleosomes and the ...
Cook, P, Marenduzzo, D
openaire   +3 more sources

SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

open access: yeseLife, 2015
Smc–ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic basis for its action, however, is only poorly understood. Here, we have established a physical
Larissa Wilhelm   +6 more
doaj   +1 more source

Bacterial chromosome segregation by the ParABS system [PDF]

open access: yesOpen Biology, 2020
Proper chromosome segregation during cell division is essential in all domains of life. In the majority of bacterial species, faithful chromosome segregation is mediated by the tripartite ParABS system, consisting of an ATPase protein ParA, a CTPase and ...
Adam S. B. Jalal, Tung B. K. Le
doaj   +1 more source

The architecture of chicken chromosome territories changes during differentiation [PDF]

open access: yes, 2004
BACKGROUND: Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory.
Bonifer, C.   +7 more
core   +4 more sources

The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice

open access: yesNature Communications, 2020
Auxin-inducible degron systems can be leaky and require high doses of auxin. Here the authors establish AID2 which uses an OsTIR1 mutant and the ligand 5-Ph-IAA to overcome these problems and establish AID-mediated target depletion in mice.
Aisha Yesbolatova   +13 more
doaj   +1 more source

The MatP/matS Site-Specific System Organizes the Terminus Region of the E. coli Chromosome into a Macrodomain [PDF]

open access: yes, 2008
The organization of the Escherichia coli chromosome into insulated macrodomains influences the segregation of sister chromatids and the mobility of chromosomal DNA.
Adachi   +39 more
core   +3 more sources

Three-dimensional chromosome organization in flowering plants.

open access: yesBriefings in Functional Genomics, 2020
Research on plant three-dimensional (3D) genome architecture made rapid progress over the past 5 years. Numerous Hi-C interaction data sets were generated in a wide range of plant species, allowing for a comprehensive overview on 3D chromosome folding ...
S. Grob
semanticscholar   +1 more source

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