Results 61 to 70 of about 4,074,715 (354)

Novel Divisome-Associated Protein Spatially Coupling the Z-Ring with the Chromosomal Replication Terminus in Caulobacter crescentus

mBio, 2020
Cell division requires proper spatial coordination with the chromosome, which undergoes dynamic changes during chromosome replication and segregation. FtsZ is a bacterial cytoskeletal protein that assembles into the Z-ring, providing a platform to build ...
Shogo Ozaki, Urs Jenal, Tsutomu Katayama
doaj   +1 more source

DNA-Membrane Anchor Facilitates Efficient Chromosome Translocation at a Distance in Bacillus subtilis

mBio, 2019
Chromosome segregation in sporulating Bacillus subtilis involves the tethering of sister chromosomes at opposite cell poles. RacA is known to mediate chromosome tethering by interacting with both centromere-like elements in the DNA and with DivIVA, a ...
Nikolai P. Radzinski, Marina Besprozvannaya, Eric L. McLean, Anusha Talwalkar, Briana M. Burton   +4 more
doaj   +1 more source

Gene silencing and large-scale domain structure of the E. coli genome

, 2012
The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression.
Lagomarsino, Marco Cosentino, Sclavi, Bianca, Zarei, Mina   +2 more
core   +2 more sources

Reduced chromosome aberration complexity in normal human bronchial epithelial cells exposed to low-LET γ-rays and high-LET α-particles [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund.Copyright © 2013 The Author(s). Purpose: Cells of the lung are at risk from exposure to low and moderate doses of ionizing radiation from a range of environmental and medical ...
Anderson, RM, Garimberti, E, Hill, MA, Themis, M   +3 more
core   +2 more sources

HupB Is a Bacterial Nucleoid-Associated Protein with an Indispensable Eukaryotic-Like Tail

mBio, 2017
In bacteria, chromosomal DNA must be efficiently compacted to fit inside the small cell compartment while remaining available for the proteins involved in replication, segregation, and transcription.
Joanna Hołówka, Damian Trojanowski, Katarzyna Ginda, Bartosz Wojtaś, Bartłomiej Gielniewski, Dagmara Jakimowicz, Jolanta Zakrzewska-Czerwińska   +6 more
doaj   +1 more source

Telomeres in Evolution and Development from Biosemiotic Perspective [PDF]

, 2007
Telomeres identify natural chromosome ends being different from broken DNA through differences in their "molecular syntax" (M.Eigen) which determines the functions of reverse transcriptase and its integrated RNA template, telomerase.
Guenther Witzany
core   +3 more sources

A Hi–C data-integrated model elucidates E. coli chromosome’s multiscale organization at various replication stages

Nucleic Acids Research, 2021
The chromosome of Escherichia coli is riddled with multi-faceted complexity. The emergence of chromosome conformation capture techniques are providing newer ways to explore chromosome organization.
A. Wasim, Ankit Gupta, Jagannath Mondal
semanticscholar   +1 more source

SMC Progressively Aligns Chromosomal Arms in Caulobacter crescentus but Is Antagonized by Convergent Transcription

Cell Reports, 2017
The structural maintenance of chromosomes (SMC) complex plays an important role in chromosome organization and segregation in most living organisms. In Caulobacter crescentus, SMC is required to align the left and the right arms of the chromosome that ...
Ngat T. Tran, Michael T. Laub, Tung B.K. Le   +2 more
doaj   +1 more source

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains [PDF]

, 2012
The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
A Kawabe, AE Hall, AF Dernburg, Alice Navrátilová, Andrea Koblížková, AW Higgins, BA Sullivan, BE Black, Beth A. Sullivan, DA Pepper, E Schroeder-Reiter, Elizabeth Schroeder-Reiter, Eva Chocholová, Gerhard Wanner, HR Lee, HS Malik, HS Malik, IC Moraes, J Macas, J Monen, Jiří Macas, JM Jiang, K Nagaki, K Nagaki, K Prufer, M Plohl, M Sanei, MD Bennett, OJ Marshall, P Binarova, P Neumann, P Neumann, P Neumann, P Novák, Pavel Neumann, PB Talbert, Petr Novák, PW Barlow, R ten Hoopen, RJ McFarlane, RK Dawe, S Heckmann, SA Ribeiro, T Haizel, Veronika Steinbauerová, W Zhang   +45 more
core   +4 more sources

Genome Organization and Chromosome Architecture [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2015
How the same DNA sequences can function in the three-dimensional architecture of interphase nucleus, fold in the very compact structure of metaphase chromosomes, and go precisely back to the original interphase architecture in the following cell cycle remains an unresolved question to this day.
openaire   +3 more sources