Decision: The art of painting chromosome loops — R0/PR4 [PDF]
Alexandre Berr, Marie‐Edith Chabouté
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Zinc‐finger MYND‐type‐containing 8 (ZMYND8) activates the transcription of CCAAT/enhancer‐binding protein epsilon by recognizing dimethylation of lysine 36 in histone H3 through its Pro‐Trp‐Trp‐Pro domain, thereby inhibiting adaptive unfolded protein response pathways to suppress the proliferation and invasion of multiple myeloma (MM) cells ...
Jiaxuan Xu+14 more
wiley +1 more source
Correction for Frönicke et al. , Towards the delineation of the ancestral eutherian genome organization: comparative genome maps of human and the African elephant ( Loxodonta africana ) generated by chromosome painting [PDF]
Lutz Frönicke+4 more
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sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin+21 more
wiley +1 more source
Comparative Karyotype of Pig and Cattle Using Whole Chromosome Painting Probes [PDF]
Annette Schmitz+5 more
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The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp+5 more
wiley +1 more source
Inverse Painting: Reconstructing The Painting Process [PDF]
Given an input painting, we reconstruct a time-lapse video of how it may have been painted. We formulate this as an autoregressive image generation problem, in which an initially blank "canvas" is iteratively updated. The model learns from real artists by training on many painting videos.
arxiv
Mouse euchromatin specific “genome-painting” with a LINE probe: A rapid method for identification and mapping of human chromosomes in mouse-human microcell hybrids by two-color FISH [PDF]
Róbert L. Katona+2 more
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This study unveiled the mechanism by which circDNA2‐educated YTHDF2 phase separation promotes PM2.5‐induced malignant transformation in HBE cells by blunting GADD45A expression, providing definitive evidence for the first time that LLPS is involved in the induction of tumorigenesis by particulate pollutants. Moreover, the clinical value of circDNA2 and
Jie Xu+5 more
wiley +1 more source
Uncovering Proximity of Chromosome Territories using Classical Algebraic Statistics [PDF]
Exchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments rejoin with other fragments from other chromosomes.
Arsuaga, Javier+3 more
core