Results 211 to 220 of about 840,795 (338)

X‐Linked Gene Dosage and SOX2 Act as Key Roadblocks for Human Germ Cell Specification in Klinefelter Syndrome

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Klinefelter syndrome‐derived iPSCs provide an excellent model for studying X chromosome inactivation and functions of escapee genes during human primordial germ cell‐like cells differentiation process. Downregulation of three X‐linked genes—IGSF1, CHRDL1, and USP9X—significantly enhances the efficiency of hPGCLCs.
Wenteng He, Qing Luo, Jian Zhao, Mengting Wang, Allan Zhao, Luohua Feng, Ahmed Reda, Eva Lindgren, Jan‐Bernd Stukenborg, Jiayu Chen, Qiaolin Deng   +10 more
wiley   +1 more source

Multidirectional chromosome painting between the Hirola antelope (Damaliscus hunteri, Alcelaphini, Bovidae), sheep and human [PDF]

, 2004
Raquel Chaves, Lutz Frönicke, Henrique Guedes‐Pinto, Johannes Wienberg   +3 more
openalex   +1 more source

Chromosomal painting of the sandpiper (Actitis macularius) detects several fissions for the Scolopacidae family (Charadriiformes) [PDF]

, 2020
Melquizedec Luiz Silva Pinheiro, Cleusa Yoshiko Nagamachi, Talita Fernanda Augusto Ribas, Cristovam Guerreiro Diniz, Patricia Caroline Mary O ́Brien, M.A. Ferguson‐Smith, Fengtang Yang, Júlio César Pieczarka   +7 more
openalex   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Phylogenomics of species from four genera of New World monkeys by flow sorting and reciprocal chromosome painting [PDF]

, 2007
Francesca Dumas, Roscoe Stanyon, Luca Sineo, Gary Stone, F. Bigoni   +4 more
openalex   +1 more source

Optimal Neutron Spectrum Database for In‐reactor 238Pu Production

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This database gives the first answer to “What is the optimal neutron spectrum for 238Pu production?” and “What is the maximum efficiency for 238Pu production?” once and for all. This database can be directly referred to for determining the optimal neutron irradiation spectrum, guiding the spectrum regulation process to improve the yield of 238Pu ...
Qingquan Pan, Xiaojing Liu, Yun Cai
wiley   +1 more source

Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion

Advanced Science, EarlyView.
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen, Zongwei Li, Zhihong Fang, Zou Li, Daoyan Yang, Yuan Li, Shurong Liu, Zhiqiang Liu, Rui Liu, Huan Liu   +9 more
wiley   +1 more source

Chromosome phylogeny of the subfamily Pitheciinae (Platyrrhini, Primates) by classic cytogenetics and chromosome painting [PDF]

, 2010
Liane FM Finotelo, Paulo José Siqueira do Amaral, Júlio César Pieczarka, Edivaldo Herculano Corrêa de Oliveira, Alcides Pissinati, Michaela Neusser, Stephan Müller, Cleusa Yoshiko Nagamachi   +7 more
openalex   +1 more source

CircMETTL6 Suppresses Ovarian Cancer Cell Growth and Metastasis Through Inhibition of GDF15 Transcription by Disrupting the NONO‐POLR2A Complex

Advanced Science, Volume 12, Issue 12, March 27, 2025.
This study identifies a novel circRNA, circMETTL6, downregulated in ovarian cancer, with its reduced expression serving as a prognostic marker for poor outcomes. CircMETTL6 acts as a tumor suppressor by interfering with NONO's interaction with POLR2A, leading to decreased GDF15 transcription.
Mengqian Yu, Mengting Wu, Tao Shen, Qiongzi Qiu, Aoran Luo, Jia Li, Xufan Li, Xiaodong Cheng, Bingjian Lu, Weiguo Lu, Pengyuan Liu, Yan Lu   +11 more
wiley   +1 more source

Production of Bovine Y Painting Probes through Chromosome Microdissection and DOP-PCR.

, 2000
Mohamed S. Hassanane, B.P. Chowdhary, I. Gustavsson   +2 more
openalex   +2 more sources